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The transforming growth factor-beta-Smad3/4 signaling pathway acts as a positive regulator for TLR2 induction by bacteria via a dual mechanism involving functional cooperation with NF-kappaB and MAPK phosphatase 1-dependent negative cross-talk with p38 MAPK.
Mikami F, Lim JH, Ishinaga H, Ha UH, Gu H, Koga T, Jono H, Kai H, Li JD. Mikami F, et al. Among authors: ha uh. J Biol Chem. 2006 Aug 4;281(31):22397-22408. doi: 10.1074/jbc.M602124200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754688 Free article.
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