Farber E - Search Results

1

The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma.

Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG. Davies BS, et al. Among authors: farber e. Mol Endocrinol. 2008 Nov;22(11):2496-504. doi: 10.1210/me.2008-0146. Epub 2008 Sep 11. Mol Endocrinol. 2008. PMID: 18787041 Free PMC article.

2

Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons.

Beigneux AP, Davies BS, Gin P, Weinstein MM, Farber E, Qiao X, Peale F, Bunting S, Walzem RL, Wong JS, Blaner WS, Ding ZM, Melford K, Wongsiriroj N, Shu X, de Sauvage F, Ryan RO, Fong LG, Bensadoun A, Young SG. Beigneux AP, et al. Among authors: farber e. Cell Metab. 2007 Apr;5(4):279-91. doi: 10.1016/j.cmet.2007.02.002. Cell Metab. 2007. PMID: 17403372 Free PMC article.

3

Eliminating the synthesis of mature lamin A reduces disease phenotypes in mice carrying a Hutchinson-Gilford progeria syndrome allele.

Yang SH, Qiao X, Farber E, Chang SY, Fong LG, Young SG. Yang SH, et al. Among authors: farber e. J Biol Chem. 2008 Mar 14;283(11):7094-9. doi: 10.1074/jbc.M708138200. Epub 2008 Jan 4. J Biol Chem. 2008. PMID: 18178963 Free article.

4

Caution! Analyze transcripts from conditional knockout alleles.

Yang SH, Bergo MO, Farber E, Qiao X, Fong LG, Young SG. Yang SH, et al. Among authors: farber e. Transgenic Res. 2009 Jun;18(3):483-9. doi: 10.1007/s11248-008-9237-9. Epub 2008 Dec 18. Transgenic Res. 2009. PMID: 19093225 Free PMC article.

5

HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.

Coffinier C, Hudon SE, Farber EA, Chang SY, Hrycyna CA, Young SG, Fong LG. Coffinier C, et al. Among authors: farber ea. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13432-7. doi: 10.1073/pnas.0704212104. Epub 2007 Jul 25. Proc Natl Acad Sci U S A. 2007. PMID: 17652517 Free PMC article.

6

Activating the synthesis of progerin, the mutant prelamin A in Hutchinson-Gilford progeria syndrome, with antisense oligonucleotides.

Fong LG, Vickers TA, Farber EA, Choi C, Yun UJ, Hu Y, Yang SH, Coffinier C, Lee R, Yin L, Davies BS, Andres DA, Spielmann HP, Bennett CF, Young SG. Fong LG, et al. Hum Mol Genet. 2009 Jul 1;18(13):2462-71. doi: 10.1093/hmg/ddp184. Epub 2009 Apr 17. Hum Mol Genet. 2009. PMID: 19376814 Free PMC article.

7

Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.

Coffinier C, Jung HJ, Li Z, Nobumori C, Yun UJ, Farber EA, Davies BS, Weinstein MM, Yang SH, Lammerding J, Farahani JN, Bentolila LA, Fong LG, Young SG. Coffinier C, et al. J Biol Chem. 2010 Jul 2;285(27):20818-26. doi: 10.1074/jbc.M110.128835. Epub 2010 May 3. J Biol Chem. 2010. PMID: 20439468 Free PMC article.

8

Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome.

Davies BS, Yang SH, Farber E, Lee R, Buck SB, Andres DA, Spielmann HP, Agnew BJ, Tamanoi F, Fong LG, Young SG. Davies BS, et al. Among authors: farber e. J Lipid Res. 2009 Jan;50(1):126-34. doi: 10.1194/jlr.M800424-JLR200. Epub 2008 Aug 29. J Lipid Res. 2009. PMID: 18757838 Free PMC article.

9

Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency.

Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG. Coffinier C, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81. doi: 10.1073/pnas.0908790107. Epub 2010 Feb 9. Proc Natl Acad Sci U S A. 2010. PMID: 20145110 Free PMC article.

10

A potent HIV protease inhibitor, darunavir, does not inhibit ZMPSTE24 or lead to an accumulation of farnesyl-prelamin A in cells.

Coffinier C, Hudon SE, Lee R, Farber EA, Nobumori C, Miner JH, Andres DA, Spielmann HP, Hrycyna CA, Fong LG, Young SG. Coffinier C, et al. Among authors: farber ea. J Biol Chem. 2008 Apr 11;283(15):9797-804. doi: 10.1074/jbc.M709629200. Epub 2008 Jan 28. J Biol Chem. 2008. PMID: 18230615 Free PMC article.

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