Mitchell RA - Search Results

1

A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells.

Winner M, Meier J, Zierow S, Rendon BE, Crichlow GV, Riggs R, Bucala R, Leng L, Smith N, Lolis E, Trent JO, Mitchell RA. Winner M, et al. Among authors: mitchell ra. Cancer Res. 2008 Sep 15;68(18):7253-7. doi: 10.1158/0008-5472.CAN-07-6227. Cancer Res. 2008. PMID: 18794110 Free PMC article.

2

Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF).

Mitchell R, Bacher M, Bernhagen J, Pushkarskaya T, Seldin MF, Bucala R. Mitchell R, et al. J Immunol. 1995 Apr 15;154(8):3863-70. J Immunol. 1995. PMID: 7706726

3

Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF).

Bernhagen J, Mitchell RA, Calandra T, Voelter W, Cerami A, Bucala R. Bernhagen J, et al. Among authors: mitchell ra. Biochemistry. 1994 Nov 29;33(47):14144-55. doi: 10.1021/bi00251a025. Biochemistry. 1994. PMID: 7947826

4

The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor.

Calandra T, Bernhagen J, Mitchell RA, Bucala R. Calandra T, et al. Among authors: mitchell ra. J Exp Med. 1994 Jun 1;179(6):1895-902. doi: 10.1084/jem.179.6.1895. J Exp Med. 1994. PMID: 8195715 Free PMC article.

5

Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action.

Mitchell RA, Metz CN, Peng T, Bucala R. Mitchell RA, et al. J Biol Chem. 1999 Jun 18;274(25):18100-6. doi: 10.1074/jbc.274.25.18100. J Biol Chem. 1999. PMID: 10364264 Free article.

6

Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF).

Mitchell RA, Bucala R. Mitchell RA, et al. Semin Cancer Biol. 2000 Oct;10(5):359-66. doi: 10.1006/scbi.2000.0328. Semin Cancer Biol. 2000. PMID: 11100884 Review.

7

Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response.

Mitchell RA, Liao H, Chesney J, Fingerle-Rowson G, Baugh J, David J, Bucala R. Mitchell RA, et al. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):345-50. doi: 10.1073/pnas.012511599. Epub 2001 Dec 26. Proc Natl Acad Sci U S A. 2002. PMID: 11756671 Free PMC article.

8

Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites.

Senter PD, Al-Abed Y, Metz CN, Benigni F, Mitchell RA, Chesney J, Han J, Gartner CG, Nelson SD, Todaro GJ, Bucala R. Senter PD, et al. Among authors: mitchell ra. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):144-9. doi: 10.1073/pnas.011569399. Epub 2002 Jan 2. Proc Natl Acad Sci U S A. 2002. PMID: 11773615 Free PMC article.

9

The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents.

Lubetsky JB, Dios A, Han J, Aljabari B, Ruzsicska B, Mitchell R, Lolis E, Al-Abed Y. Lubetsky JB, et al. J Biol Chem. 2002 Jul 12;277(28):24976-82. doi: 10.1074/jbc.M203220200. Epub 2002 May 7. J Biol Chem. 2002. PMID: 11997397 Free article.

10

Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity.

Dios A, Mitchell RA, Aljabari B, Lubetsky J, O'Connor K, Liao H, Senter PD, Manogue KR, Lolis E, Metz C, Bucala R, Callaway DJ, Al-Abed Y. Dios A, et al. Among authors: mitchell ra. J Med Chem. 2002 Jun 6;45(12):2410-6. doi: 10.1021/jm010534q. J Med Chem. 2002. PMID: 12036350

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