Boudjelal M - Search Results

1

Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy.

Owen BM, Van Mil SW, Boudjelal M, McLay I, Cairns W, Elias E, White R, Williamson C, Dixon PH. Owen BM, et al. Among authors: boudjelal m. Xenobiotica. 2008 Oct;38(10):1289-97. doi: 10.1080/00498250802426114. Xenobiotica. 2008. PMID: 18800312

2

Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function.

Milona A, Owen BM, Cobbold JF, Willemsen EC, Cox IJ, Boudjelal M, Cairns W, Schoonjans K, Taylor-Robinson SD, Klomp LW, Parker MG, White R, van Mil SW, Williamson C. Milona A, et al. Among authors: boudjelal m. Hepatology. 2010 Oct;52(4):1341-9. doi: 10.1002/hep.23849. Hepatology. 2010. PMID: 20842631

3

Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.

Owen BM, Milona A, van Mil S, Clements P, Holder J, Boudjelal M, Cairns W, Parker M, White R, Williamson C. Owen BM, et al. Among authors: boudjelal m. Drug Metab Dispos. 2010 Jan;38(1):143-9. doi: 10.1124/dmd.109.029306. Drug Metab Dispos. 2010. PMID: 19797606 Free PMC article.

4

The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.

Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, Cairns W, Schoonjans K, Milligan S, Parker M, White R, Williamson C. Milona A, et al. Among authors: boudjelal m. Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G151-8. doi: 10.1152/ajpgi.00336.2009. Epub 2009 Oct 8. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 19815629 Free PMC article.

5

The application of BacMam technology in nuclear receptor drug discovery.

Boudjelal M, Mason SJ, Katso RM, Fleming JM, Parham JH, Condreay JP, Merrihew RV, Cairns WJ. Boudjelal M, et al. Biotechnol Annu Rev. 2005;11:101-25. doi: 10.1016/S1387-2656(05)11003-5. Biotechnol Annu Rev. 2005. PMID: 16216775 Review.

6

Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.

Biggadike K, Boudjelal M, Clackers M, Coe DM, Demaine DA, Hardy GW, Humphreys D, Inglis GG, Johnston MJ, Jones HT, House D, Loiseau R, Needham D, Skone PA, Uings I, Veitch G, Weingarten GG, McLay IM, Macdonald SJ. Biggadike K, et al. Among authors: boudjelal m. J Med Chem. 2007 Dec 27;50(26):6519-34. doi: 10.1021/jm070778w. Epub 2007 Nov 27. J Med Chem. 2007. PMID: 18038970

7

Optimized chemical probes for REV-ERBα.

Trump RP, Bresciani S, Cooper AW, Tellam JP, Wojno J, Blaikley J, Orband-Miller LA, Kashatus JA, Boudjelal M, Dawson HC, Loudon A, Ray D, Grant D, Farrow SN, Willson TM, Tomkinson NC. Trump RP, et al. Among authors: boudjelal m. J Med Chem. 2013 Jun 13;56(11):4729-37. doi: 10.1021/jm400458q. Epub 2013 May 23. J Med Chem. 2013. PMID: 23656296 Free PMC article.

8

Nuclear Receptors Are Differentially Expressed and Activated in KAIMRC1 Compared to MCF7 and MDA-MB231 Breast Cancer Cells.

Nehdi A, Ali R, Alhallaj A, Alzahrani H, Samman N, Mashhour A, Baz O, Barhoumi T, Alghanem B, Khan A, Alriyees L, Boudjelal M. Nehdi A, et al. Among authors: boudjelal m. Molecules. 2019 May 28;24(11):2028. doi: 10.3390/molecules24112028. Molecules. 2019. PMID: 31141879 Free PMC article.

9

Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.

Skepner J, Ramesh R, Trocha M, Schmidt D, Baloglu E, Lobera M, Carlson T, Hill J, Orband-Miller LA, Barnes A, Boudjelal M, Sundrud M, Ghosh S, Yang J. Skepner J, et al. Among authors: boudjelal m. J Immunol. 2014 Mar 15;192(6):2564-75. doi: 10.4049/jimmunol.1302190. Epub 2014 Feb 10. J Immunol. 2014. PMID: 24516202

10

High Throughput Screening Assay to Identify Modulators of IL-17 Expression.

Boudjelal M, Ruiz-Avendano AM, Colmenarejo G, Senar-Sancho SA, Barnes A, Harrison SA. Boudjelal M, et al. Comb Chem High Throughput Screen. 2017;20(9):804-819. doi: 10.2174/1386207320666170602091308. Comb Chem High Throughput Screen. 2017. PMID: 28571538

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