Nijman IJ - Search Results

1

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel R, Toonen PW, Verheul M, van Roekel HS, Nijman IJ, Guryev V, Cuppen E. van Boxtel R, et al. Among authors: nijman ij. BMC Genomics. 2008 Oct 7;9:460. doi: 10.1186/1471-2164-9-460. BMC Genomics. 2008. PMID: 18840264 Free PMC article.

2

Systematic generation of in vivo G protein-coupled receptor mutants in the rat.

van Boxtel R, Vroling B, Toonen P, Nijman IJ, van Roekel H, Verheul M, Baakman C, Guryev V, Vriend G, Cuppen E. van Boxtel R, et al. Among authors: nijman ij. Pharmacogenomics J. 2011 Oct;11(5):326-36. doi: 10.1038/tpj.2010.44. Epub 2010 Jun 8. Pharmacogenomics J. 2011. PMID: 20531371 Free PMC article.

3

Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene.

Cuppen E, Gort E, Hazendonk E, Mudde J, van de Belt J, Nijman IJ, Guryev V, Plasterk RH. Cuppen E, et al. Among authors: nijman ij. Genome Res. 2007 May;17(5):649-58. doi: 10.1101/gr.6080607. Epub 2007 Apr 6. Genome Res. 2007. PMID: 17416746 Free PMC article.

4

A genome-wide SNP panel for mapping and association studies in the rat.

Nijman IJ, Kuipers S, Verheul M, Guryev V, Cuppen E. Nijman IJ, et al. BMC Genomics. 2008 Feb 25;9:95. doi: 10.1186/1471-2164-9-95. BMC Genomics. 2008. PMID: 18298839 Free PMC article.

5

Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line.

Feitsma H, de Bruijn E, van de Belt J, Nijman IJ, Cuppen E. Feitsma H, et al. Among authors: nijman ij. Mutagenesis. 2008 Jul;23(4):325-9. doi: 10.1093/mutage/gen019. Epub 2008 May 9. Mutagenesis. 2008. PMID: 18469325

6

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples.

Nijman IJ, Mokry M, van Boxtel R, Toonen P, de Bruijn E, Cuppen E. Nijman IJ, et al. Nat Methods. 2010 Nov;7(11):913-5. doi: 10.1038/nmeth.1516. Epub 2010 Oct 17. Nat Methods. 2010. PMID: 20953175

7

Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.

Feitsma H, Kuiper RV, Korving J, Nijman IJ, Cuppen E. Feitsma H, et al. Among authors: nijman ij. Cancer Res. 2008 Jul 1;68(13):5059-66. doi: 10.1158/0008-5472.CAN-08-0019. Cancer Res. 2008. PMID: 18593904

8

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries.

Mokry M, Feitsma H, Nijman IJ, de Bruijn E, van der Zaag PJ, Guryev V, Cuppen E. Mokry M, et al. Among authors: nijman ij. Nucleic Acids Res. 2010 Jun;38(10):e116. doi: 10.1093/nar/gkq072. Epub 2010 Feb 17. Nucleic Acids Res. 2010. PMID: 20164091 Free PMC article.

9

Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach.

Mokry M, Nijman IJ, van Dijken A, Benjamins R, Heidstra R, Scheres B, Cuppen E. Mokry M, et al. Among authors: nijman ij. BMC Genomics. 2011 May 20;12:256. doi: 10.1186/1471-2164-12-256. BMC Genomics. 2011. PMID: 21599977 Free PMC article.

10

A hypomorphic mutation in Lpin1 induces progressively improving neuropathy and lipodystrophy in the rat.

Mul JD, Nadra K, Jagalur NB, Nijman IJ, Toonen PW, Médard JJ, Grès S, de Bruin A, Han GS, Brouwers JF, Carman GM, Saulnier-Blache JS, Meijer D, Chrast R, Cuppen E. Mul JD, et al. Among authors: nijman ij. J Biol Chem. 2011 Jul 29;286(30):26781-93. doi: 10.1074/jbc.M110.197947. Epub 2011 Jun 1. J Biol Chem. 2011. PMID: 21715287 Free PMC article.

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