van Roekel HS - Search Results

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Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel R, Toonen PW, Verheul M, van Roekel HS, Nijman IJ, Guryev V, Cuppen E. van Boxtel R, et al. Among authors: van roekel hs. BMC Genomics. 2008 Oct 7;9:460. doi: 10.1186/1471-2164-9-460. BMC Genomics. 2008. PMID: 18840264 Free PMC article.

Systematic generation of in vivo G protein-coupled receptor mutants in the rat.

van Boxtel R, Vroling B, Toonen P, Nijman IJ, van Roekel H, Verheul M, Baakman C, Guryev V, Vriend G, Cuppen E. van Boxtel R, et al. Pharmacogenomics J. 2011 Oct;11(5):326-36. doi: 10.1038/tpj.2010.44. Epub 2010 Jun 8. Pharmacogenomics J. 2011. PMID: 20531371 Free PMC article.

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.

van Boxtel R, Toonen PW, van Roekel HS, Verheul M, Smits BM, Korving J, de Bruin A, Cuppen E. van Boxtel R, et al. Among authors: van roekel hs. Carcinogenesis. 2008 Jun;29(6):1290-7. doi: 10.1093/carcin/bgn094. Epub 2008 Apr 15. Carcinogenesis. 2008. PMID: 18417481

Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing.

Harakalova M, Mokry M, Hrdlickova B, Renkens I, Duran K, van Roekel H, Lansu N, van Roosmalen M, de Bruijn E, Nijman IJ, Kloosterman WP, Cuppen E. Harakalova M, et al. Nat Protoc. 2011 Nov 3;6(12):1870-86. doi: 10.1038/nprot.2011.396. Nat Protoc. 2011. PMID: 22051800

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