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Population pharmacokinetic model for a novel oral hypoglycemic formed in vivo: comparing the use of active metabolite data alone versus using data of upstream and downstream metabolites.
Kastrissios H, Walker JR, Carrothers TJ, Kshirsagar S, Khariton T, Habtemariam B, Mager DE, Rohatagi S. Kastrissios H, et al. Among authors: khariton t. J Clin Pharmacol. 2012 Mar;52(3):404-15. doi: 10.1177/0091270010396373. Epub 2011 Mar 21. J Clin Pharmacol. 2012. PMID: 21422240
Population PK Modeling and Target Attainment Simulations to Support Dosing of Ceftaroline Fosamil in Pediatric Patients With Acute Bacterial Skin and Skin Structure Infections and Community-Acquired Bacterial Pneumonia.
Riccobene TA, Khariton T, Knebel W, Das S, Li J, Jandourek A, Carrothers TJ, Bradley JS. Riccobene TA, et al. Among authors: khariton t. J Clin Pharmacol. 2017 Mar;57(3):345-355. doi: 10.1002/jcph.809. Epub 2016 Sep 27. J Clin Pharmacol. 2017. PMID: 27510635
Population Pharmacokinetics of Cariprazine and its Major Metabolites.
Periclou A, Phillips L, Ghahramani P, Kapás M, Carrothers T, Khariton T. Periclou A, et al. Among authors: khariton t. Eur J Drug Metab Pharmacokinet. 2021 Jan;46(1):53-69. doi: 10.1007/s13318-020-00650-4. Eur J Drug Metab Pharmacokinet. 2021. PMID: 33141308 Free PMC article.
Pharmacokinetic-pharmacodynamic analysis for efficacy of ceftaroline fosamil in patients with acute bacterial skin and skin structure infections.
Bhavnani SM, Hammel JP, Van Wart SA, Rubino CM, Reynolds DK, Forrest A, Drusano GL, Khariton T, Friedland HD, Riccobene TA, Ambrose PG. Bhavnani SM, et al. Among authors: khariton t. Antimicrob Agents Chemother. 2015 Jan;59(1):372-80. doi: 10.1128/AAC.02531-14. Epub 2014 Nov 3. Antimicrob Agents Chemother. 2015. PMID: 25367904 Free PMC article. Clinical Trial.
12 results