Chen CT - Search Results

1

IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.

Lee DF, Kuo HP, Chen CT, Wei Y, Chou CK, Hung JY, Yen CJ, Hung MC. Lee DF, et al. Among authors: chen ct. Int J Mol Med. 2008 Nov;22(5):633-8. doi: 10.3892/ijmm_00000065. Int J Mol Med. 2008. PMID: 18949383 Free PMC article.

2

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.

Lee DF, Kuo HP, Chen CT, Hsu JM, Chou CK, Wei Y, Sun HL, Li LY, Ping B, Huang WC, He X, Hung JY, Lai CC, Ding Q, Su JL, Yang JY, Sahin AA, Hortobagyi GN, Tsai FJ, Tsai CH, Hung MC. Lee DF, et al. Among authors: chen ct. Cell. 2007 Aug 10;130(3):440-55. doi: 10.1016/j.cell.2007.05.058. Cell. 2007. PMID: 17693255 Free article.

3

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

Yen CJ, Izzo JG, Lee DF, Guha S, Wei Y, Wu TT, Chen CT, Kuo HP, Hsu JM, Sun HL, Chou CK, Buttar NS, Wang KK, Huang P, Ajani J, Hung MC. Yen CJ, et al. Among authors: chen ct. Cancer Res. 2008 Apr 15;68(8):2632-40. doi: 10.1158/0008-5472.CAN-07-5460. Cancer Res. 2008. PMID: 18413730 Free PMC article.

4

KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.

Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, Chang YH, Tsai SF, Li LY, Hung MC. Lee DF, et al. Among authors: chen ct. Mol Cell. 2009 Oct 9;36(1):131-40. doi: 10.1016/j.molcel.2009.07.025. Mol Cell. 2009. PMID: 19818716 Free PMC article.

5

ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.

Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, Xing G, Zhao Y, Lin CH, Tsai SF, Fidler IJ, Hung MC. Kuo HP, et al. Among authors: chen ct. Sci Signal. 2010 Feb 9;3(108):ra9. doi: 10.1126/scisignal.2000590. Sci Signal. 2010. PMID: 20145209 Free PMC article.

6

IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression.

Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, Dhar D, Karin M, Chen CH, Hung MC. Liu M, et al. Among authors: chen ct, chen ch. Mol Cell. 2012 Jan 27;45(2):171-84. doi: 10.1016/j.molcel.2011.11.018. Epub 2011 Dec 22. Mol Cell. 2012. PMID: 22196886 Free PMC article.

7

Targeting the IKKβ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer.

Chen CT, Du Y, Yamaguchi H, Hsu JM, Kuo HP, Hortobagyi GN, Hung MC. Chen CT, et al. Mol Cancer Ther. 2012 Oct;11(10):2212-21. doi: 10.1158/1535-7163.MCT-12-0180. Epub 2012 Jul 23. Mol Cancer Ther. 2012. PMID: 22826466 Free PMC article.

8

Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization.

Ding Q, He X, Hsu JM, Xia W, Chen CT, Li LY, Lee DF, Liu JC, Zhong Q, Wang X, Hung MC. Ding Q, et al. Among authors: chen ct. Mol Cell Biol. 2007 Jun;27(11):4006-17. doi: 10.1128/MCB.00620-06. Epub 2007 Mar 26. Mol Cell Biol. 2007. PMID: 17387146 Free PMC article.

9

Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

Ding Q, He X, Xia W, Hsu JM, Chen CT, Li LY, Lee DF, Yang JY, Xie X, Liu JC, Hung MC. Ding Q, et al. Among authors: chen ct. Cancer Res. 2007 May 15;67(10):4564-71. doi: 10.1158/0008-5472.CAN-06-1788. Epub 2007 May 10. Cancer Res. 2007. PMID: 17495324

10

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation.

Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, Lin CY, Lee HJ, Wang YN, Liu M, Liao HW, Shi B, Lai CC, Bedford MT, Tsai CH, Hung MC. Hsu JM, et al. Among authors: chen ct. Nat Cell Biol. 2011 Feb;13(2):174-81. doi: 10.1038/ncb2158. Epub 2011 Jan 23. Nat Cell Biol. 2011. PMID: 21258366 Free PMC article.

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