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New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening.
Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, Arthur WT, Moon RT. Major MB, et al. Among authors: anastas j. Sci Signal. 2008 Nov 11;1(45):ra12. doi: 10.1126/scisignal.2000037. Sci Signal. 2008. PMID: 19001663
WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors.
Anastas JN, Kulikauskas RM, Tamir T, Rizos H, Long GV, von Euw EM, Yang PT, Chen HW, Haydu L, Toroni RA, Lucero OM, Chien AJ, Moon RT. Anastas JN, et al. J Clin Invest. 2014 Jul;124(7):2877-90. doi: 10.1172/JCI70156. Epub 2014 May 27. J Clin Invest. 2014. PMID: 24865425 Free PMC article.
Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.
Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y. Anastas JN, et al. Cancer Cell. 2019 Nov 11;36(5):528-544.e10. doi: 10.1016/j.ccell.2019.09.005. Epub 2019 Oct 17. Cancer Cell. 2019. PMID: 31631026 Free article.
Histone Lysine Demethylase Inhibitors.
Jambhekar A, Anastas JN, Shi Y. Jambhekar A, et al. Cold Spring Harb Perspect Med. 2017 Jan 3;7(1):a026484. doi: 10.1101/cshperspect.a026484. Cold Spring Harb Perspect Med. 2017. PMID: 28049654 Free PMC article. Review.
RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma.
Jiao F, Li Z, He C, Xu W, Yang G, Liu T, Shen H, Cai J, Anastas JN, Mao Y, Yu Y, Lan F, Shi YG, Jones C, Xu Y, Baker SJ, Shi Y, Guo R. Jiao F, et al. Among authors: anastas jn. Sci Adv. 2020 Jul 17;6(29):eaba2113. doi: 10.1126/sciadv.aba2113. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832624 Free PMC article.
30 results