Wickman GR - Search Results

1

Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

Hu-Lowe DD, Zou HY, Grazzini ML, Hallin ME, Wickman GR, Amundson K, Chen JH, Rewolinski DA, Yamazaki S, Wu EY, McTigue MA, Murray BW, Kania RS, O'Connor P, Shalinsky DR, Bender SL. Hu-Lowe DD, et al. Among authors: wickman gr. Clin Cancer Res. 2008 Nov 15;14(22):7272-83. doi: 10.1158/1078-0432.CCR-08-0652. Clin Cancer Res. 2008. PMID: 19010843

2

Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies.

Hu-Lowe DD, Chen E, Zhang L, Watson KD, Mancuso P, Lappin P, Wickman G, Chen JH, Wang J, Jiang X, Amundson K, Simon R, Erbersdobler A, Bergqvist S, Feng Z, Swanson TA, Simmons BH, Lippincott J, Casperson GF, Levin WJ, Stampino CG, Shalinsky DR, Ferrara KW, Fiedler W, Bertolini F. Hu-Lowe DD, et al. Cancer Res. 2011 Feb 15;71(4):1362-73. doi: 10.1158/0008-5472.CAN-10-1451. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212415 Free PMC article.

3

Dual functional monoclonal antibody PF-04605412 targets integrin alpha5beta1 and elicits potent antibody-dependent cellular cytotoxicity.

Li G, Zhang L, Chen E, Wang J, Jiang X, Chen JH, Wickman G, Amundson K, Bergqvist S, Zobel J, Buckman D, Baxi SM, Bender SL, Casperson GF, Hu-Lowe DD. Li G, et al. Cancer Res. 2010 Dec 15;70(24):10243-54. doi: 10.1158/0008-5472.CAN-10-1996. Cancer Res. 2010. PMID: 21159645

4

Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm.

Wickman G, Lan C, Vollrath B. Wickman G, et al. Circ Res. 2003 Apr 18;92(7):809-16. doi: 10.1161/01.RES.0000066663.12256.B2. Epub 2003 Mar 13. Circ Res. 2003. PMID: 12637369

5

Effects of tamoxifen on oxyhemoglobin-induced cerebral vasoconstriction.

Wickman G, Vollrath B. Wickman G, et al. Eur J Pharmacol. 2000 Feb 25;390(1-2):181-4. doi: 10.1016/s0014-2999(99)00907-3. Eur J Pharmacol. 2000. PMID: 10708722

6

The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm.

Wickman G, Nessim MA, Cook DA, Vollrath B. Wickman G, et al. Br J Pharmacol. 2001 May;133(1):5-12. doi: 10.1038/sj.bjp.0704025. Br J Pharmacol. 2001. PMID: 11325788 Free PMC article.

7

Modulation of oxyhemoglobin-induced protein kinase C activation by tamoxifen.

Wickman G, Cook D, Vollrath B. Wickman G, et al. Proc West Pharmacol Soc. 2001;44:129-31. Proc West Pharmacol Soc. 2001. PMID: 11793958 No abstract available.

8

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells.

Scott RW, Hooper S, Crighton D, Li A, König I, Munro J, Trivier E, Wickman G, Morin P, Croft DR, Dawson J, Machesky L, Anderson KI, Sahai EA, Olson MF. Scott RW, et al. J Cell Biol. 2010 Oct 4;191(1):169-85. doi: 10.1083/jcb.201002041. Epub 2010 Sep 27. J Cell Biol. 2010. PMID: 20876278 Free PMC article.

9

Blebs produced by actin-myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs.

Wickman GR, Julian L, Mardilovich K, Schumacher S, Munro J, Rath N, Zander SA, Mleczak A, Sumpton D, Morrice N, Bienvenut WV, Olson MF. Wickman GR, et al. Cell Death Differ. 2013 Oct;20(10):1293-305. doi: 10.1038/cdd.2013.69. Epub 2013 Jun 21. Cell Death Differ. 2013. PMID: 23787996 Free PMC article.

10

Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression.

Julian L, Naylor G, Wickman GR, Rath N, Castino G, Stevenson D, Bryson S, Munro J, McGarry L, Mullin M, Rice A, Del Río Hernández A, Olson MF. Julian L, et al. Among authors: wickman gr. Elife. 2021 Apr 19;10:e61983. doi: 10.7554/eLife.61983. Elife. 2021. PMID: 33871359 Free PMC article.

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