Govender U - Search Results

1

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

Burrows JF, Kelvin AA, McFarlane C, Burden RE, McGrattan MJ, De la Vega M, Govender U, Quinn DJ, Dib K, Gadina M, Scott CJ, Johnston JA. Burrows JF, et al. Among authors: govender u. J Biol Chem. 2009 Apr 3;284(14):9587-95. doi: 10.1074/jbc.M807216200. Epub 2009 Feb 2. J Biol Chem. 2009. PMID: 19188362 Free PMC article.

2

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

de la Vega M, Burrows JF, McFarlane C, Govender U, Scott CJ, Johnston JA. de la Vega M, et al. Among authors: govender u. J Biol Chem. 2010 Apr 16;285(16):12028-36. doi: 10.1074/jbc.M109.081448. Epub 2010 Feb 10. J Biol Chem. 2010. PMID: 20147298 Free PMC article.

3

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

McFarlane C, Kelvin AA, de la Vega M, Govender U, Scott CJ, Burrows JF, Johnston JA. McFarlane C, et al. Among authors: govender u. Cancer Res. 2010 Apr 15;70(8):3329-39. doi: 10.1158/0008-5472.CAN-09-4152. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388806

4

A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17.

Jaworski J, Govender U, McFarlane C, de la Vega M, Greene MK, Rawlings ND, Johnston JA, Scott CJ, Burrows JF. Jaworski J, et al. Among authors: govender u. Biochem J. 2014 Jan 15;457(2):289-300. doi: 10.1042/BJ20131213. Biochem J. 2014. PMID: 24134311 Free article.

5

Correlation of mycobacterium tuberculosis specific and non-specific quantitative Th1 T-cell responses with bacillary load in a high burden setting.

Theron G, Peter J, Lenders L, van Zyl-Smit R, Meldau R, Govender U, Dheda K. Theron G, et al. Among authors: govender u. PLoS One. 2012;7(5):e37436. doi: 10.1371/journal.pone.0037436. Epub 2012 May 22. PLoS One. 2012. PMID: 22629395 Free PMC article.

6

The diagnostic accuracy of urine-based Xpert MTB/RIF in HIV-infected hospitalized patients who are smear-negative or sputum scarce.

Peter JG, Theron G, Muchinga TE, Govender U, Dheda K. Peter JG, et al. Among authors: govender u. PLoS One. 2012;7(7):e39966. doi: 10.1371/journal.pone.0039966. Epub 2012 Jul 9. PLoS One. 2012. PMID: 22815718 Free PMC article. Clinical Trial.

7

Accuracy and impact of Xpert MTB/RIF for the diagnosis of smear-negative or sputum-scarce tuberculosis using bronchoalveolar lavage fluid.

Theron G, Peter J, Meldau R, Khalfey H, Gina P, Matinyena B, Lenders L, Calligaro G, Allwood B, Symons G, Govender U, Setshedi M, Dheda K. Theron G, et al. Among authors: govender u. Thorax. 2013 Nov;68(11):1043-51. doi: 10.1136/thoraxjnl-2013-203485. Epub 2013 Jun 29. Thorax. 2013. PMID: 23811536 Free PMC article.

8

Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicentre randomised controlled trial.

Calligaro GL, Zijenah LS, Peter JG, Theron G, Buser V, McNerney R, Bara W, Bandason T, Govender U, Tomasicchio M, Smith L, Mayosi BM, Dheda K. Calligaro GL, et al. Among authors: govender u. Lancet Infect Dis. 2017 Apr;17(4):441-450. doi: 10.1016/S1473-3099(16)30384-X. Epub 2017 Jan 5. Lancet Infect Dis. 2017. PMID: 28063795 Clinical Trial.

9

Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-γ for the evaluation of pleural tuberculosis: a prospective cohort study.

Meldau R, Peter J, Theron G, Calligaro G, Allwood B, Symons G, Khalfey H, Ntombenhle G, Govender U, Binder A, van Zyl-Smit R, Dheda K. Meldau R, et al. Among authors: govender u. BMC Pulm Med. 2014 Apr 8;14:58. doi: 10.1186/1471-2466-14-58. BMC Pulm Med. 2014. PMID: 24708530 Free PMC article.

10

Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous pericarditis compared to adenosine deaminase and unstimulated interferon-γ in a high burden setting: a prospective study.

Pandie S, Peter JG, Kerbelker ZS, Meldau R, Theron G, Govender U, Ntsekhe M, Dheda K, Mayosi BM. Pandie S, et al. Among authors: govender u. BMC Med. 2014 Jun 18;12:101. doi: 10.1186/1741-7015-12-101. BMC Med. 2014. PMID: 24942470 Free PMC article.

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