Grefhorst A - Search Results

1

An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice.

van Dijk TH, Grefhorst A, Oosterveer MH, Bloks VW, Staels B, Reijngoud DJ, Kuipers F. van Dijk TH, et al. Among authors: grefhorst a. J Biol Chem. 2009 Apr 17;284(16):10315-23. doi: 10.1074/jbc.M807317200. Epub 2009 Feb 9. J Biol Chem. 2009. PMID: 19204003 Free PMC article.

2

A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice.

van Dijk TH, Laskewitz AJ, Grefhorst A, Boer TS, Bloks VW, Kuipers F, Groen AK, Reijngoud DJ. van Dijk TH, et al. Among authors: grefhorst a. Lab Anim. 2013 Apr;47(2):79-88. doi: 10.1177/0023677212473714. Epub 2013 Mar 14. Lab Anim. 2013. PMID: 23492513

3

Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.

Grefhorst A, Elzinga BM, Voshol PJ, Plösch T, Kok T, Bloks VW, van der Sluijs FH, Havekes LM, Romijn JA, Verkade HJ, Kuipers F. Grefhorst A, et al. J Biol Chem. 2002 Sep 13;277(37):34182-90. doi: 10.1074/jbc.M204887200. Epub 2002 Jul 3. J Biol Chem. 2002. PMID: 12097330 Free article.

4

The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition.

Duran-Sandoval D, Cariou B, Percevault F, Hennuyer N, Grefhorst A, van Dijk TH, Gonzalez FJ, Fruchart JC, Kuipers F, Staels B. Duran-Sandoval D, et al. Among authors: grefhorst a. J Biol Chem. 2005 Aug 19;280(33):29971-9. doi: 10.1074/jbc.M501931200. Epub 2005 May 16. J Biol Chem. 2005. PMID: 15899888 Free article.

5

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B. Cariou B, et al. Among authors: grefhorst a. J Biol Chem. 2006 Apr 21;281(16):11039-49. doi: 10.1074/jbc.M510258200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446356 Free article.

6

Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice.

Oosterveer MH, van Dijk TH, Grefhorst A, Bloks VW, Havinga R, Kuipers F, Reijngoud DJ. Oosterveer MH, et al. Among authors: grefhorst a. J Biol Chem. 2008 Sep 12;283(37):25437-25445. doi: 10.1074/jbc.M801922200. Epub 2008 Jul 8. J Biol Chem. 2008. PMID: 18611859 Free article.

7

Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice.

Oosterveer MH, Grefhorst A, van Dijk TH, Havinga R, Staels B, Kuipers F, Groen AK, Reijngoud DJ. Oosterveer MH, et al. Among authors: grefhorst a. J Biol Chem. 2009 Dec 4;284(49):34036-44. doi: 10.1074/jbc.M109.051052. Epub 2009 Oct 2. J Biol Chem. 2009. PMID: 19801551 Free PMC article.

8

Enhanced glucose cycling and suppressed de novo synthesis of glucose-6-phosphate result in a net unchanged hepatic glucose output in ob/ob mice.

Bandsma RH, Grefhorst A, van Dijk TH, van der Sluijs FH, Hammer A, Reijngoud DJ, Kuipers F. Bandsma RH, et al. Among authors: grefhorst a. Diabetologia. 2004 Nov;47(11):2022-31. doi: 10.1007/s00125-004-1571-8. Epub 2004 Dec 1. Diabetologia. 2004. PMID: 15599701

9

Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice.

Grefhorst A, van Dijk TH, Hammer A, van der Sluijs FH, Havinga R, Havekes LM, Romijn JA, Groot PH, Reijngoud DJ, Kuipers F. Grefhorst A, et al. Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E829-38. doi: 10.1152/ajpendo.00165.2005. Epub 2005 Jun 7. Am J Physiol Endocrinol Metab. 2005. PMID: 15941783 Free article.

10

Transient impairment of the adaptive response to fasting in FXR-deficient mice.

Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk T, Grefhorst A, Bouchaert E, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B. Cariou B, et al. Among authors: grefhorst a. FEBS Lett. 2005 Aug 1;579(19):4076-80. doi: 10.1016/j.febslet.2005.06.033. FEBS Lett. 2005. PMID: 16023103 Free article.

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