Parthasarathy G - Search Results

1

Synthesis and biological evaluation of platensimycin analogs.

Shen HC, Ding FX, Singh SB, Parthasarathy G, Soisson SM, Ha SN, Chen X, Kodali S, Wang J, Dorso K, Tata JR, Hammond ML, Maccoss M, Colletti SL. Shen HC, et al. Among authors: parthasarathy g. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1623-7. doi: 10.1016/j.bmcl.2009.02.006. Epub 2009 Feb 7. Bioorg Med Chem Lett. 2009. PMID: 19233644

2

Platensimycin is a selective FabF inhibitor with potent antibiotic properties.

Wang J, Soisson SM, Young K, Shoop W, Kodali S, Galgoci A, Painter R, Parthasarathy G, Tang YS, Cummings R, Ha S, Dorso K, Motyl M, Jayasuriya H, Ondeyka J, Herath K, Zhang C, Hernandez L, Allocco J, Basilio A, Tormo JR, Genilloud O, Vicente F, Pelaez F, Colwell L, Lee SH, Michael B, Felcetto T, Gill C, Silver LL, Hermes JD, Bartizal K, Barrett J, Schmatz D, Becker JW, Cully D, Singh SB. Wang J, et al. Among authors: parthasarathy g. Nature. 2006 May 18;441(7091):358-61. doi: 10.1038/nature04784. Nature. 2006. PMID: 16710421

3

Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.

Singh SB, Ondeyka JG, Herath KB, Zhang C, Jayasuriya H, Zink DL, Parthasarathy G, Becker JW, Wang J, Soisson SM. Singh SB, et al. Among authors: parthasarathy g. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4756-9. doi: 10.1016/j.bmcl.2009.06.061. Epub 2009 Jun 17. Bioorg Med Chem Lett. 2009. PMID: 19581087

4

Surface-entropy reduction approaches to manipulate crystal forms of beta-ketoacyl acyl carrier protein synthase II from Streptococcus pneumoniae.

Parthasarathy G, Cummings R, Becker JW, Soisson SM. Parthasarathy G, et al. Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):141-8. doi: 10.1107/S090744490705559X. Epub 2008 Jan 16. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18219113

5

Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation.

Soisson SM, Parthasarathy G, Adams AD, Sahoo S, Sitlani A, Sparrow C, Cui J, Becker JW. Soisson SM, et al. Among authors: parthasarathy g. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5337-42. doi: 10.1073/pnas.0710981105. Epub 2008 Apr 7. Proc Natl Acad Sci U S A. 2008. PMID: 18391212 Free PMC article.

6

Transition state structure of arginine kinase: implications for catalysis of bimolecular reactions.

Zhou G, Somasundaram T, Blanc E, Parthasarathy G, Ellington WR, Chapman MS. Zhou G, et al. Among authors: parthasarathy g. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8449-54. doi: 10.1073/pnas.95.15.8449. Proc Natl Acad Sci U S A. 1998. PMID: 9671698 Free PMC article.

7

Disordered to ordered folding in the regulation of diphtheria toxin repressor activity.

Twigg PD, Parthasarathy G, Guerrero L, Logan TM, Caspar DL. Twigg PD, et al. Among authors: parthasarathy g. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11259-64. doi: 10.1073/pnas.191354798. Proc Natl Acad Sci U S A. 2001. PMID: 11572979 Free PMC article.

8

Expression, purification from inclusion bodies, and crystal characterization of a transition state analog complex of arginine kinase: a model for studying phosphagen kinases.

Zhou G, Parthasarathy G, Somasundaram T, Ables A, Roy L, Strong SJ, Ellington WR, Chapman MS. Zhou G, et al. Among authors: parthasarathy g. Protein Sci. 1997 Feb;6(2):444-9. doi: 10.1002/pro.5560060222. Protein Sci. 1997. PMID: 9041648 Free PMC article.

9

Expression, purification, and characterization of avian Thy-1 from Lec1 mammalian and Tn5 insect cells.

Mehndiratta P, Walton WJ, Hare JT, Pulido S, Parthasarathy G, Emmett MR, Marshall AG, Logan TM. Mehndiratta P, et al. Among authors: parthasarathy g. Protein Expr Purif. 2004 Feb;33(2):274-87. doi: 10.1016/j.pep.2003.10.011. Protein Expr Purif. 2004. PMID: 14711516

10

New crystal forms of the motile major sperm protein (MSP) of Ascaris suum.

Bullock TL, Parthasarathy G, King KL, Kent HM, Roberts TM, Stewart M. Bullock TL, et al. Among authors: parthasarathy g. J Struct Biol. 1996 May-Jun;116(3):432-7. doi: 10.1006/jsbi.1996.0061. J Struct Biol. 1996. PMID: 8813002

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