Wang S - Search Results

1

Decoding the cryptic active conformation of a protein by synthetic photoscanning: insulin inserts a detachable arm between receptor domains.

Xu B, Huang K, Chu YC, Hu SQ, Nakagawa S, Wang S, Wang RY, Whittaker J, Katsoyannis PG, Weiss MA. Xu B, et al. Among authors: wang s, wang ry. J Biol Chem. 2009 May 22;284(21):14597-608. doi: 10.1074/jbc.M900087200. Epub 2009 Mar 25. J Biol Chem. 2009. PMID: 19321435 Free PMC article.

2

Diabetes-associated mutations in insulin identify invariant receptor contacts.

Xu B, Hu SQ, Chu YC, Wang S, Wang RY, Nakagawa SH, Katsoyannis PG, Weiss MA. Xu B, et al. Among authors: wang s, wang ry. Diabetes. 2004 Jun;53(6):1599-602. doi: 10.2337/diabetes.53.6.1599. Diabetes. 2004. PMID: 15161767

3

How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.

Huang K, Xu B, Hu SQ, Chu YC, Hua QX, Qu Y, Li B, Wang S, Wang RY, Nakagawa SH, Theede AM, Whittaker J, De Meyts P, Katsoyannis PG, Weiss MA. Huang K, et al. Among authors: wang s, wang ry. J Mol Biol. 2004 Aug 6;341(2):529-50. doi: 10.1016/j.jmb.2004.05.023. J Mol Biol. 2004. PMID: 15276842

4

Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin Wakayama.

Wan ZL, Huang K, Xu B, Hu SQ, Wang S, Chu YC, Katsoyannis PG, Weiss MA. Wan ZL, et al. Among authors: wang s. Biochemistry. 2005 Apr 5;44(13):5000-16. doi: 10.1021/bi047585k. Biochemistry. 2005. PMID: 15794638

5

Chiral mutagenesis of insulin. Contribution of the B20-B23 beta-turn to activity and stability.

Nakagawa SH, Hua QX, Hu SQ, Jia W, Wang S, Katsoyannis PG, Weiss MA. Nakagawa SH, et al. Among authors: wang s. J Biol Chem. 2006 Aug 4;281(31):22386-22396. doi: 10.1074/jbc.M603547200. Epub 2006 Jun 2. J Biol Chem. 2006. PMID: 16751187 Free article.

6

Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain.

Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Hua QX, et al. Among authors: wang s. J Biol Chem. 2006 Aug 25;281(34):24900-9. doi: 10.1074/jbc.M602691200. Epub 2006 Jun 8. J Biol Chem. 2006. PMID: 16762918 Free article.

7

Enhancing the activity of a protein by stereospecific unfolding: conformational life cycle of insulin and its evolutionary origins.

Hua QX, Xu B, Huang K, Hu SQ, Nakagawa S, Jia W, Wang S, Whittaker J, Katsoyannis PG, Weiss MA. Hua QX, et al. Among authors: wang s. J Biol Chem. 2009 May 22;284(21):14586-96. doi: 10.1074/jbc.M900085200. Epub 2009 Mar 25. J Biol Chem. 2009. PMID: 19321436 Free PMC article.

8

Insulin analogues with modifications in the beta-turn of the B-chain.

Wang SH, Hu SQ, Burke GT, Katsoyannis PG. Wang SH, et al. J Protein Chem. 1991 Jun;10(3):313-24. doi: 10.1007/BF01025630. J Protein Chem. 1991. PMID: 1910463

9

Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.

Hua QX, Hu SQ, Jia W, Chu YC, Burke GT, Wang SH, Wang RY, Katsoyannis PG, Weiss MA. Hua QX, et al. Among authors: wang sh, wang ry. J Mol Biol. 1998 Mar 20;277(1):103-18. doi: 10.1006/jmbi.1997.1574. J Mol Biol. 1998. PMID: 9514738

10

Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.

Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA. Hua QX, et al. Among authors: wang sh. J Mol Biol. 1996 Nov 29;264(2):390-403. doi: 10.1006/jmbi.1996.0648. J Mol Biol. 1996. PMID: 8951384

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