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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.
Calzascia T, Pellegrini M, Lin A, Garza KM, Elford AR, Shahinian A, Ohashi PS, Mak TW. Calzascia T, et al. Among authors: pellegrini m. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2999-3004. doi: 10.1073/pnas.0712135105. Epub 2008 Feb 14. Proc Natl Acad Sci U S A. 2008. PMID: 18287017 Free PMC article.
IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW. Pellegrini M, et al. Cell. 2011 Feb 18;144(4):601-13. doi: 10.1016/j.cell.2011.01.011. Epub 2011 Feb 3. Cell. 2011. PMID: 21295337 Free article.
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
Wang C, McPherson AJ, Jones RB, Kawamura KS, Lin GH, Lang PA, Ambagala T, Pellegrini M, Calzascia T, Aidarus N, Elford AR, Yue FY, Kremmer E, Kovacs CM, Benko E, Tremblay C, Routy JP, Bernard NF, Ostrowski MA, Ohashi PS, Watts TH. Wang C, et al. Among authors: pellegrini m. J Exp Med. 2012 Jan 16;209(1):77-91. doi: 10.1084/jem.20110675. Epub 2011 Dec 19. J Exp Med. 2012. PMID: 22184633 Free PMC article.
ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system.
Lin AE, Ebert G, Ow Y, Preston SP, Toe JG, Cooney JP, Scott HW, Sasaki M, Saibil SD, Dissanayake D, Kim RH, Wakeham A, You-Ten A, Shahinian A, Duncan G, Silvester J, Ohashi PS, Mak TW, Pellegrini M. Lin AE, et al. Among authors: pellegrini m. Nat Immunol. 2013 Jan;14(1):27-33. doi: 10.1038/ni.2478. Epub 2012 Nov 25. Nat Immunol. 2013. PMID: 23179078
Cellular FLICE-inhibitory protein is required for T cell survival and cycling.
Chau H, Wong V, Chen NJ, Huang HL, Lin WJ, Mirtsos C, Elford AR, Bonnard M, Wakeham A, You-Ten AI, Lemmers B, Salmena L, Pellegrini M, Hakem R, Mak TW, Ohashi P, Yeh WC. Chau H, et al. Among authors: pellegrini m. J Exp Med. 2005 Aug 1;202(3):405-13. doi: 10.1084/jem.20050118. Epub 2005 Jul 25. J Exp Med. 2005. PMID: 16043518 Free PMC article.
1,719 results