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Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Sparsø T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O. Sparsø T, et al. Diabetologia. 2009 Jul;52(7):1308-14. doi: 10.1007/s00125-009-1362-3. Epub 2009 Apr 29. Diabetologia. 2009. PMID: 19404609
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.
Larsen LH, Rose CS, Sparsø T, Overgaard J, Torekov SS, Grarup N, Jensen DP, Albrechtsen A, Andersen G, Ek J, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O. Larsen LH, et al. Among authors: sparso t. Int J Obes (Lond). 2007 Feb;31(2):365-70. doi: 10.1038/sj.ijo.0803408. Epub 2006 Jun 6. Int J Obes (Lond). 2007. PMID: 16755280
A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.
Boesgaard TW, Castella SI, Andersen G, Albrechtsen A, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O. Boesgaard TW, et al. Among authors: sparso t. Diabet Med. 2007 Jul;24(7):702-6. doi: 10.1111/j.1464-5491.2007.02110.x. Epub 2007 Apr 24. Diabet Med. 2007. PMID: 17459095
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Sparsø T, Andersen G, Nielsen T, Burgdorf KS, Gjesing AP, Nielsen AL, Albrechtsen A, Rasmussen SS, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O. Sparsø T, et al. Diabetologia. 2008 Jan;51(1):70-5. doi: 10.1007/s00125-007-0865-z. Epub 2007 Nov 16. Diabetologia. 2008. PMID: 18008060
80 results