Rusyn I - Search Results

1

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.

Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW. Harrill AH, et al. Among authors: rusyn i. Genome Res. 2009 Sep;19(9):1507-15. doi: 10.1101/gr.090241.108. Epub 2009 May 5. Genome Res. 2009. PMID: 19416960 Free PMC article.

2

Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver.

Powell CL, Kosyk O, Ross PK, Schoonhoven R, Boysen G, Swenberg JA, Heinloth AN, Boorman GA, Cunningham ML, Paules RS, Rusyn I. Powell CL, et al. Among authors: rusyn i. Toxicol Sci. 2006 Sep;93(1):213-22. doi: 10.1093/toxsci/kfl030. Epub 2006 Jun 2. Toxicol Sci. 2006. PMID: 16751229 Free PMC article.

3

WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.

Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I. Woods CG, et al. Among authors: rusyn i. Toxicol Sci. 2007 Aug;98(2):366-74. doi: 10.1093/toxsci/kfm104. Epub 2007 May 5. Toxicol Sci. 2007. PMID: 17483499

4

Genome-level analysis of genetic regulation of liver gene expression networks.

Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I. Gatti D, et al. Among authors: rusyn i. Hepatology. 2007 Aug;46(2):548-57. doi: 10.1002/hep.21682. Hepatology. 2007. PMID: 17542012 Free PMC article.

5

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.

Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, Kayton RJ, Kerr KF, Kosyk O, Lobenhofer EK, Sieber SO, Vliet PA, Weis BK, Wolfinger R, Woods CG, Freedman JH, Linney E, Kaufmann WK, Kavanagh TJ, Paules RS, Rusyn I, Samson LD, Spencer PS, Suk W, Tennant RJ, Zarbl H; Members of the Toxicogenomics Research Consortium. Beyer RP, et al. Among authors: rusyn i. Toxicol Sci. 2007 Sep;99(1):326-37. doi: 10.1093/toxsci/kfm150. Epub 2007 Jun 11. Toxicol Sci. 2007. PMID: 17562736

6

Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows.

Roberts A, McMillan L, Wang W, Parker J, Rusyn I, Threadgill D. Roberts A, et al. Among authors: rusyn i. Bioinformatics. 2007 Jul 1;23(13):i401-7. doi: 10.1093/bioinformatics/btm220. Bioinformatics. 2007. PMID: 17646323

7

Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.

Woods CG, Kosyk O, Bradford BU, Ross PK, Burns AM, Cunningham ML, Qu P, Ibrahim JG, Rusyn I. Woods CG, et al. Among authors: rusyn i. Toxicol Appl Pharmacol. 2007 Dec 15;225(3):267-77. doi: 10.1016/j.taap.2007.08.028. Epub 2007 Sep 16. Toxicol Appl Pharmacol. 2007. PMID: 17950772 Free PMC article.

8

Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease.

Bradford BU, O'Connell TM, Han J, Kosyk O, Shymonyak S, Ross PK, Winnike J, Kono H, Rusyn I. Bradford BU, et al. Among authors: rusyn i. Toxicol Appl Pharmacol. 2008 Oct 15;232(2):236-43. doi: 10.1016/j.taap.2008.06.022. Epub 2008 Jul 12. Toxicol Appl Pharmacol. 2008. PMID: 18674555 Free PMC article.

9

Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity.

Harrill AH, Rusyn I. Harrill AH, et al. Among authors: rusyn i. Expert Opin Drug Metab Toxicol. 2008 Nov;4(11):1379-89. doi: 10.1517/17425255.4.11.1379. Expert Opin Drug Metab Toxicol. 2008. PMID: 18950280 Free PMC article. Review.

10

Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver.

Ross PK, Woods CG, Bradford BU, Kosyk O, Gatti DM, Cunningham ML, Rusyn I. Ross PK, et al. Among authors: rusyn i. Toxicol Appl Pharmacol. 2009 Mar 1;235(2):199-207. doi: 10.1016/j.taap.2008.12.011. Epub 2008 Dec 24. Toxicol Appl Pharmacol. 2009. PMID: 19136022 Free PMC article.

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