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Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
Orozco G, Hinks A, Eyre S, Ke X, Gibbons LJ, Bowes J, Flynn E, Martin P; Wellcome Trust Case Control Consortium; YEAR consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Barton A, Worthington J. Orozco G, et al. Among authors: morgan aw. Hum Mol Genet. 2009 Jul 15;18(14):2693-9. doi: 10.1093/hmg/ddp193. Epub 2009 May 5. Hum Mol Genet. 2009. PMID: 19417005 Free PMC article.
Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B.
Morgan AW, Barrett JH, Griffiths B, Subramanian D, Robinson JI, Keyte VH, Ali M, Jones EA, Old RW, Ponchel F, Boylston AW, Situnayake RD, Markham AF, Emery P, Isaacs JD. Morgan AW, et al. Arthritis Res Ther. 2006;8(1):R5. doi: 10.1186/ar1847. Arthritis Res Ther. 2006. PMID: 16356189 Free PMC article.
Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis.
Maxwell JR, Potter C, Hyrich KL; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG. Maxwell JR, et al. Among authors: morgan aw. Hum Mol Genet. 2008 Nov 15;17(22):3532-8. doi: 10.1093/hmg/ddn245. Epub 2008 Aug 19. Hum Mol Genet. 2008. PMID: 18713756
Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J. Barton A, et al. Among authors: morgan aw. Nat Genet. 2008 Oct;40(10):1156-9. doi: 10.1038/ng.218. Epub 2008 Sep 14. Nat Genet. 2008. PMID: 18794857 Free PMC article.
Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.
Bowes JD, Potter C, Gibbons LJ, Hyrich K, Plant D, Morgan AW, Wilson AG, Isaacs JD, Worthington J, Barton A; BRAGGSS. Bowes JD, et al. Among authors: morgan aw. Pharmacogenet Genomics. 2009 Apr;19(4):319-23. doi: 10.1097/FPC.0b013e328328d51f. Pharmacogenet Genomics. 2009. PMID: 19262425
Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.
Barton A, Eyre S, Ke X, Hinks A, Bowes J, Flynn E, Martin P; YEAR Consortium; BIRAC Consortium; Wilson AG, Morgan AW, Emery P, Steer S, Hocking LJ, Reid DM, Harrison P, Wordsworth P, Thomson W, Worthington J. Barton A, et al. Among authors: morgan aw. Hum Mol Genet. 2009 Jul 1;18(13):2518-22. doi: 10.1093/hmg/ddp177. Epub 2009 Apr 9. Hum Mol Genet. 2009. PMID: 19359276 Free PMC article.
175 results