Yang XW - Search Results

1

DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation.

Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G. Hutnick LK, et al. Among authors: yang xw. Hum Mol Genet. 2009 Aug 1;18(15):2875-88. doi: 10.1093/hmg/ddp222. Epub 2009 May 10. Hum Mol Genet. 2009. PMID: 19433415 Free PMC article.

2

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism.

Peñagarikano O, Lázaro MT, Lu XH, Gordon A, Dong H, Lam HA, Peles E, Maidment NT, Murphy NP, Yang XW, Golshani P, Geschwind DH. Peñagarikano O, et al. Among authors: yang xw. Sci Transl Med. 2015 Jan 21;7(271):271ra8. doi: 10.1126/scitranslmed.3010257. Sci Transl Med. 2015. PMID: 25609168 Free PMC article.

3

Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.

Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Gu X, et al. Among authors: yang xw. Neuron. 2005 May 5;46(3):433-44. doi: 10.1016/j.neuron.2005.03.025. Neuron. 2005. PMID: 15882643 Free article.

4

Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease.

Spampanato J, Gu X, Yang XW, Mody I. Spampanato J, et al. Among authors: yang xw. Neuroscience. 2008 Dec 2;157(3):606-20. doi: 10.1016/j.neuroscience.2008.09.020. Epub 2008 Sep 18. Neuroscience. 2008. PMID: 18854207 Free PMC article.

5

Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression.

Pouladi MA, Xie Y, Skotte NH, Ehrnhoefer DE, Graham RK, Kim JE, Bissada N, Yang XW, Paganetti P, Friedlander RM, Leavitt BR, Hayden MR. Pouladi MA, et al. Among authors: yang xw. Hum Mol Genet. 2010 Apr 15;19(8):1528-38. doi: 10.1093/hmg/ddq026. Epub 2010 Jan 22. Hum Mol Genet. 2010. PMID: 20097678 Free PMC article.

6

Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration.

Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Tao J, et al. Among authors: yang xw. J Neurosci. 2011 Jun 1;31(22):8306-19. doi: 10.1523/JNEUROSCI.0567-11.2011. J Neurosci. 2011. PMID: 21632951 Free PMC article.

7

Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease.

Estrada-Sánchez AM, Burroughs CL, Cavaliere S, Barton SJ, Chen S, Yang XW, Rebec GV. Estrada-Sánchez AM, et al. Among authors: yang xw. J Neurosci. 2015 Mar 11;35(10):4440-51. doi: 10.1523/JNEUROSCI.2812-14.2015. J Neurosci. 2015. PMID: 25762686 Free PMC article.

8

Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.

Chandra A, Sharma A, Calingasan NY, White JM, Shurubor Y, Yang XW, Beal MF, Johri A. Chandra A, et al. Among authors: yang xw. Hum Mol Genet. 2016 Jun 1;25(11):2269-2282. doi: 10.1093/hmg/ddw095. Epub 2016 Mar 22. Hum Mol Genet. 2016. PMID: 27008868 Free PMC article.

9

Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels.

Horvath S, Langfelder P, Kwak S, Aaronson J, Rosinski J, Vogt TF, Eszes M, Faull RL, Curtis MA, Waldvogel HJ, Choi OW, Tung S, Vinters HV, Coppola G, Yang XW. Horvath S, et al. Among authors: yang xw. Aging (Albany NY). 2016 Jul;8(7):1485-512. doi: 10.18632/aging.101005. Aging (Albany NY). 2016. PMID: 27479945 Free PMC article.

10

A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.

Southwell AL, Skotte NH, Villanueva EB, Østergaard ME, Gu X, Kordasiewicz HB, Kay C, Cheung D, Xie Y, Waltl S, Dal Cengio L, Findlay-Black H, Doty CN, Petoukhov E, Iworima D, Slama R, Ooi J, Pouladi MA, Yang XW, Swayze EE, Seth PP, Hayden MR. Southwell AL, et al. Among authors: yang xw. Hum Mol Genet. 2017 Mar 15;26(6):1115-1132. doi: 10.1093/hmg/ddx021. Hum Mol Genet. 2017. PMID: 28104789

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