Hymowitz SG - Search Results

1

Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.

Ndubaku C, Varfolomeev E, Wang L, Zobel K, Lau K, Elliott LO, Maurer B, Fedorova AV, Dynek JN, Koehler M, Hymowitz SG, Tsui V, Deshayes K, Fairbrother WJ, Flygare JA, Vucic D. Ndubaku C, et al. Among authors: hymowitz sg. ACS Chem Biol. 2009 Jul 17;4(7):557-66. doi: 10.1021/cb900083m. ACS Chem Biol. 2009. PMID: 19492850

2

Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.

Yan M, Wang LC, Hymowitz SG, Schilbach S, Lee J, Goddard A, de Vos AM, Gao WQ, Dixit VM. Yan M, et al. Among authors: hymowitz sg. Science. 2000 Oct 20;290(5491):523-7. doi: 10.1126/science.290.5491.523. Science. 2000. PMID: 11039935

3

BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site.

Gordon NC, Pan B, Hymowitz SG, Yin J, Kelley RF, Cochran AG, Yan M, Dixit VM, Fairbrother WJ, Starovasnik MA. Gordon NC, et al. Among authors: hymowitz sg. Biochemistry. 2003 May 27;42(20):5977-83. doi: 10.1021/bi034017g. Biochemistry. 2003. PMID: 12755599

4

Activation of the proapoptotic death receptor DR5 by oligomeric peptide and antibody agonists.

Li B, Russell SJ, Compaan DM, Totpal K, Marsters SA, Ashkenazi A, Cochran AG, Hymowitz SG, Sidhu SS. Li B, et al. Among authors: hymowitz sg. J Mol Biol. 2006 Aug 18;361(3):522-36. doi: 10.1016/j.jmb.2006.06.042. Epub 2006 Jul 7. J Mol Biol. 2006. PMID: 16859704

5

Delineation of the cell-extrinsic apoptosis pathway in the zebrafish.

Eimon PM, Kratz E, Varfolomeev E, Hymowitz SG, Stern H, Zha J, Ashkenazi A. Eimon PM, et al. Among authors: hymowitz sg. Cell Death Differ. 2006 Oct;13(10):1619-30. doi: 10.1038/sj.cdd.4402015. Epub 2006 Aug 4. Cell Death Differ. 2006. PMID: 16888647

6

Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.

Gordon NC, Lien S, Johnson J, Wallweber HJ, Tran T, Currell B, Mathieu M, Quan C, Starovasnik MA, Hymowitz SG, Kelley RF. Gordon NC, et al. Among authors: hymowitz sg. J Mol Biol. 2010 Feb 12;396(1):166-77. doi: 10.1016/j.jmb.2009.11.041. Epub 2009 Nov 26. J Mol Biol. 2010. PMID: 19945466

7

Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling.

Bosanac I, Wertz IE, Pan B, Yu C, Kusam S, Lam C, Phu L, Phung Q, Maurer B, Arnott D, Kirkpatrick DS, Dixit VM, Hymowitz SG. Bosanac I, et al. Among authors: hymowitz sg. Mol Cell. 2010 Nov 24;40(4):548-57. doi: 10.1016/j.molcel.2010.10.009. Mol Cell. 2010. PMID: 21095585 Free article.

8

Modulation of K11-linkage formation by variable loop residues within UbcH5A.

Bosanac I, Phu L, Pan B, Zilberleyb I, Maurer B, Dixit VM, Hymowitz SG, Kirkpatrick DS. Bosanac I, et al. Among authors: hymowitz sg. J Mol Biol. 2011 May 6;408(3):420-31. doi: 10.1016/j.jmb.2011.03.011. Epub 2011 Mar 10. J Mol Biol. 2011. PMID: 21396940

9

Preparation of distinct ubiquitin chain reagents of high purity and yield.

Dong KC, Helgason E, Yu C, Phu L, Arnott DP, Bosanac I, Compaan DM, Huang OW, Fedorova AV, Kirkpatrick DS, Hymowitz SG, Dueber EC. Dong KC, et al. Among authors: hymowitz sg. Structure. 2011 Aug 10;19(8):1053-63. doi: 10.1016/j.str.2011.06.010. Structure. 2011. PMID: 21827942 Free article.

10

Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.

Dueber EC, Schoeffler AJ, Lingel A, Elliott JM, Fedorova AV, Giannetti AM, Zobel K, Maurer B, Varfolomeev E, Wu P, Wallweber HJ, Hymowitz SG, Deshayes K, Vucic D, Fairbrother WJ. Dueber EC, et al. Among authors: hymowitz sg. Science. 2011 Oct 21;334(6054):376-80. doi: 10.1126/science.1207862. Science. 2011. PMID: 22021857

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