Vucic D - Search Results

1

Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.

Ndubaku C, Varfolomeev E, Wang L, Zobel K, Lau K, Elliott LO, Maurer B, Fedorova AV, Dynek JN, Koehler M, Hymowitz SG, Tsui V, Deshayes K, Fairbrother WJ, Flygare JA, Vucic D. Ndubaku C, et al. Among authors: vucic d. ACS Chem Biol. 2009 Jul 17;4(7):557-66. doi: 10.1021/cb900083m. ACS Chem Biol. 2009. PMID: 19492850

2

Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP.

Seshagiri S, Vucic D, Lee J, Dixit VM. Seshagiri S, et al. Among authors: vucic d. J Biol Chem. 1999 Dec 17;274(51):36769-73. doi: 10.1074/jbc.274.51.36769. J Biol Chem. 1999. PMID: 10593985 Free article.

3

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas.

Vucic D, Stennicke HR, Pisabarro MT, Salvesen GS, Dixit VM. Vucic D, et al. Curr Biol. 2000 Nov 2;10(21):1359-66. doi: 10.1016/s0960-9822(00)00781-8. Curr Biol. 2000. PMID: 11084335 Free article.

4

SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP).

Vucic D, Deshayes K, Ackerly H, Pisabarro MT, Kadkhodayan S, Fairbrother WJ, Dixit VM. Vucic D, et al. J Biol Chem. 2002 Apr 5;277(14):12275-9. doi: 10.1074/jbc.M112045200. Epub 2002 Jan 18. J Biol Chem. 2002. PMID: 11801603 Free article.

5

Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).

Franklin MC, Kadkhodayan S, Ackerly H, Alexandru D, Distefano MD, Elliott LO, Flygare JA, Mausisa G, Okawa DC, Ong D, Vucic D, Deshayes K, Fairbrother WJ. Franklin MC, et al. Among authors: vucic d. Biochemistry. 2003 Jul 15;42(27):8223-31. doi: 10.1021/bi034227t. Biochemistry. 2003. PMID: 12846571

6

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

Vucic D, Franklin MC, Wallweber HJ, Das K, Eckelman BP, Shin H, Elliott LO, Kadkhodayan S, Deshayes K, Salvesen GS, Fairbrother WJ. Vucic D, et al. Biochem J. 2005 Jan 1;385(Pt 1):11-20. doi: 10.1042/BJ20041108. Biochem J. 2005. PMID: 15485396 Free PMC article.

7

Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.

Varfolomeev E, Maecker H, Sharp D, Lawrence D, Renz M, Vucic D, Ashkenazi A. Varfolomeev E, et al. Among authors: vucic d. J Biol Chem. 2005 Dec 9;280(49):40599-608. doi: 10.1074/jbc.M509560200. Epub 2005 Oct 15. J Biol Chem. 2005. PMID: 16227629 Free article.

8

The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.

Varfolomeev E, Wayson SM, Dixit VM, Fairbrother WJ, Vucic D. Varfolomeev E, et al. Among authors: vucic d. J Biol Chem. 2006 Sep 29;281(39):29022-9. doi: 10.1074/jbc.M605116200. Epub 2006 Aug 4. J Biol Chem. 2006. PMID: 16891304 Free article.

9

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.

Zobel K, Wang L, Varfolomeev E, Franklin MC, Elliott LO, Wallweber HJ, Okawa DC, Flygare JA, Vucic D, Fairbrother WJ, Deshayes K. Zobel K, et al. Among authors: vucic d. ACS Chem Biol. 2006 Sep 19;1(8):525-33. doi: 10.1021/cb600276q. ACS Chem Biol. 2006. PMID: 17168540

10

The inhibitor of apoptosis proteins as therapeutic targets in cancer.

Vucic D, Fairbrother WJ. Vucic D, et al. Clin Cancer Res. 2007 Oct 15;13(20):5995-6000. doi: 10.1158/1078-0432.CCR-07-0729. Clin Cancer Res. 2007. PMID: 17947460 Review.

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