Czarna A - Search Results

1

Rapid and efficient hydrophilicity tuning of p53/mdm2 antagonists.

Srivastava S, Beck B, Wang W, Czarna A, Holak TA, Dömling A. Srivastava S, et al. Among authors: czarna a. J Comb Chem. 2009 Jul-Aug;11(4):631-9. doi: 10.1021/cc9000218. J Comb Chem. 2009. PMID: 19548636 Free PMC article.

2

Molecular basis for the inhibition of p53 by Mdmx.

Popowicz GM, Czarna A, Rothweiler U, Szwagierczak A, Krajewski M, Weber L, Holak TA. Popowicz GM, et al. Among authors: czarna a. Cell Cycle. 2007 Oct 1;6(19):2386-92. doi: 10.4161/cc.6.19.4740. Epub 2007 Oct 12. Cell Cycle. 2007. PMID: 17938582

3

Isoquinolin-1-one inhibitors of the MDM2-p53 interaction.

Rothweiler U, Czarna A, Krajewski M, Ciombor J, Kalinski C, Khazak V, Ross G, Skobeleva N, Weber L, Holak TA. Rothweiler U, et al. Among authors: czarna a. ChemMedChem. 2008 Jul;3(7):1118-28. doi: 10.1002/cmdc.200800025. ChemMedChem. 2008. PMID: 18428185

4

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.

Popowicz GM, Czarna A, Holak TA. Popowicz GM, et al. Among authors: czarna a. Cell Cycle. 2008 Aug;7(15):2441-3. doi: 10.4161/cc.6365. Epub 2008 May 27. Cell Cycle. 2008. PMID: 18677113

5

NMR screening for lead compounds using tryptophan-mutated proteins.

Rothweiler U, Czarna A, Weber L, Popowicz GM, Brongel K, Kowalska K, Orth M, Stemmann O, Holak TA. Rothweiler U, et al. Among authors: czarna a. J Med Chem. 2008 Aug 28;51(16):5035-42. doi: 10.1021/jm8002813. Epub 2008 Aug 5. J Med Chem. 2008. PMID: 18680271

6

High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx.

Czarna A, Popowicz GM, Pecak A, Wolf S, Dubin G, Holak TA. Czarna A, et al. Cell Cycle. 2009 Apr 15;8(8):1176-84. doi: 10.4161/cc.8.8.8185. Epub 2009 Apr 16. Cell Cycle. 2009. PMID: 19305137

7

Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery.

Popowicz GM, Czarna A, Wolf S, Wang K, Wang W, Dömling A, Holak TA. Popowicz GM, et al. Among authors: czarna a. Cell Cycle. 2010 Mar 15;9(6):1104-11. doi: 10.4161/cc.9.6.10956. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20237429

8

Robust generation of lead compounds for protein-protein interactions by computational and MCR chemistry: p53/Hdm2 antagonists.

Czarna A, Beck B, Srivastava S, Popowicz GM, Wolf S, Huang Y, Bista M, Holak TA, Dömling A. Czarna A, et al. Angew Chem Int Ed Engl. 2010 Jul 19;49(31):5352-6. doi: 10.1002/anie.201001343. Angew Chem Int Ed Engl. 2010. PMID: 20575124 Free PMC article. No abstract available.

9

Mechanism of MyD88S mediated signal termination.

Pustelny K, Kuska K, Gorecki A, Musielak B, Dobosz E, Wladyka B, Koziel J, Czarna A, Holak T, Dubin G. Pustelny K, et al. Among authors: czarna a. Cell Commun Signal. 2022 Jan 20;20(1):10. doi: 10.1186/s12964-021-00811-1. Cell Commun Signal. 2022. PMID: 35057808 Free PMC article.

10

Imaging of Clear Cell Renal Carcinoma with Immune Checkpoint Targeting Aptamer-Based Probe.

Malicki S, Pucelik B, Żyła E, Benedyk-Machaczka M, Gałan W, Golda A, Sochaj-Gregorczyk A, Kamińska M, Encarnação JC, Chruścicka B, Marti HP, Chen TJ, Magiera-Mularz K, Zięba B, Holak TA, Dąbrowski JM, Czarna A, Kozieł J, Mydel P, Dubin G. Malicki S, et al. Among authors: czarna a. Pharmaceuticals (Basel). 2022 Jun 1;15(6):697. doi: 10.3390/ph15060697. Pharmaceuticals (Basel). 2022. PMID: 35745616 Free PMC article.

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