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Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity.
Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Cubillos-Ruiz JR, et al. Among authors: gewirtz at. J Clin Invest. 2009 Aug;119(8):2231-44. doi: 10.1172/JCI37716. Epub 2009 Jul 13. J Clin Invest. 2009. PMID: 19620771 Free PMC article.
Deletion of TLR5 results in spontaneous colitis in mice.
Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT. Vijay-Kumar M, et al. Among authors: gewirtz at. J Clin Invest. 2007 Dec;117(12):3909-21. doi: 10.1172/JCI33084. J Clin Invest. 2007. PMID: 18008007 Free PMC article.
Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.
Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD Jr, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, Kennett MJ, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M. Singh V, et al. Among authors: gewirtz at. Cell. 2018 Oct 18;175(3):679-694.e22. doi: 10.1016/j.cell.2018.09.004. Cell. 2018. PMID: 30340040 Free PMC article.
271 results