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Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity.
Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Cubillos-Ruiz JR, et al. Among authors: scarlett uk. J Clin Invest. 2009 Aug;119(8):2231-44. doi: 10.1172/JCI37716. Epub 2009 Jul 13. J Clin Invest. 2009. PMID: 19620771 Free PMC article.
Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer.
Cubillos-Ruiz JR, Baird JR, Tesone AJ, Rutkowski MR, Scarlett UK, Camposeco-Jacobs AL, Anadon-Arnillas J, Harwood NM, Korc M, Fiering SN, Sempere LF, Conejo-Garcia JR. Cubillos-Ruiz JR, et al. Among authors: scarlett uk. Cancer Res. 2012 Apr 1;72(7):1683-93. doi: 10.1158/0008-5472.CAN-11-3160. Epub 2012 Feb 3. Cancer Res. 2012. PMID: 22307839 Free PMC article.
PILAR is a novel modulator of human T-cell expansion.
Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Engle XA, Rigby WF, Pioli PA, Guyre PM, Conejo-Garcia JR. Huarte E, et al. Among authors: scarlett uk. Blood. 2008 Aug 15;112(4):1259-68. doi: 10.1182/blood-2007-12-130773. Epub 2008 Jun 12. Blood. 2008. PMID: 18550855 Free PMC article.
Ovarian cancer progression is controlled by phenotypic changes in dendritic cells.
Scarlett UK, Rutkowski MR, Rauwerdink AM, Fields J, Escovar-Fadul X, Baird J, Cubillos-Ruiz JR, Jacobs AC, Gonzalez JL, Weaver J, Fiering S, Conejo-Garcia JR. Scarlett UK, et al. J Exp Med. 2012 Mar 12;209(3):495-506. doi: 10.1084/jem.20111413. Epub 2012 Feb 20. J Exp Med. 2012. PMID: 22351930 Free PMC article.
14 results