Ryeom S - Search Results

1

The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.

Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T. Minami T, et al. Among authors: ryeom s. J Clin Invest. 2009 Aug;119(8):2257-70. doi: 10.1172/JCI35738. Epub 2009 Jul 13. J Clin Invest. 2009. PMID: 19620774 Free PMC article.

2

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.

Baek KH, Zaslavsky A, Lynch RC, Britt C, Okada Y, Siarey RJ, Lensch MW, Park IH, Yoon SS, Minami T, Korenberg JR, Folkman J, Daley GQ, Aird WC, Galdzicki Z, Ryeom S. Baek KH, et al. Among authors: ryeom s. Nature. 2009 Jun 25;459(7250):1126-30. doi: 10.1038/nature08062. Epub 2009 May 20. Nature. 2009. PMID: 19458618 Free PMC article.

3

The calcineurin-NFAT pathway negatively regulates megakaryopoiesis.

Zaslavsky A, Chou ST, Schadler K, Lieberman A, Pimkin M, Kim YJ, Baek KH, Aird WC, Weiss MJ, Ryeom S. Zaslavsky A, et al. Among authors: ryeom s. Blood. 2013 Apr 18;121(16):3205-15. doi: 10.1182/blood-2012-04-421172. Epub 2013 Feb 27. Blood. 2013. PMID: 23446734 Free PMC article.

4

The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases.

Minami T, Jiang S, Schadler K, Suehiro J, Osawa T, Oike Y, Miura M, Naito M, Kodama T, Ryeom S. Minami T, et al. Among authors: ryeom s. Cell Rep. 2013 Aug 29;4(4):709-23. doi: 10.1016/j.celrep.2013.07.021. Epub 2013 Aug 15. Cell Rep. 2013. PMID: 23954784 Free PMC article.

5

Loss of Down Syndrome Critical Region-1 Mediated-Hypercholesterolemia Accelerates Corneal Opacity Via Pathological Neovessel Formation.

Muramatsu M, Nakagawa S, Osawa T, Toyono T, Uemura A, Kidoya H, Takakura N, Usui T, Ryeom S, Minami T. Muramatsu M, et al. Among authors: ryeom s. Arterioscler Thromb Vasc Biol. 2020 Oct;40(10):2425-2439. doi: 10.1161/ATVBAHA.120.315003. Epub 2020 Aug 13. Arterioscler Thromb Vasc Biol. 2020. PMID: 32787520 Free PMC article.

6

Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background.

Muramatsu M, Osawa T, Miyamura Y, Nakagawa S, Tanaka T, Kodama T, Aburatani H, Sakai J, Ryeom S, Minami T. Muramatsu M, et al. Among authors: ryeom s. J Biol Chem. 2021 Jan-Jun;296:100697. doi: 10.1016/j.jbc.2021.100697. Epub 2021 Apr 23. J Biol Chem. 2021. PMID: 33895138 Free PMC article.

7

The cautionary tale of side effects of chronic Notch1 inhibition.

Ryeom SW. Ryeom SW. J Clin Invest. 2011 Feb;121(2):508-9. doi: 10.1172/JCI45976. Epub 2011 Jan 25. J Clin Invest. 2011. PMID: 21266769 Free PMC article.

8

Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors.

Baek KH, Bhang D, Zaslavsky A, Wang LC, Vachani A, Kim CF, Albelda SM, Evan GI, Ryeom S. Baek KH, et al. Among authors: ryeom s. J Clin Invest. 2013 Oct;123(10):4375-89. doi: 10.1172/JCI67465. Epub 2013 Sep 9. J Clin Invest. 2013. PMID: 24018559 Free PMC article.

9

Down syndrome candidate region 1-like 1 (DSCR1-L1) mimics the inhibitory effects of DSCR1 on calcineurin signaling in endothelial cells and inhibits angiogenesis.

Gollogly LK, Ryeom SW, Yoon SS. Gollogly LK, et al. Among authors: ryeom sw. J Surg Res. 2007 Sep;142(1):129-36. doi: 10.1016/j.jss.2006.10.011. Epub 2007 Jul 5. J Surg Res. 2007. PMID: 17610901 Free PMC article.

10

Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth.

Ryeom S, Baek KH, Rioth MJ, Lynch RC, Zaslavsky A, Birsner A, Yoon SS, McKeon F. Ryeom S, et al. Cancer Cell. 2008 May;13(5):420-31. doi: 10.1016/j.ccr.2008.02.018. Cancer Cell. 2008. PMID: 18455125 Free article.

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