Liu Z - Search Results

1

Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells.

Fan HY, Liu Z, Paquet M, Wang J, Lydon JP, DeMayo FJ, Richards JS. Fan HY, et al. Among authors: liu z. Cancer Res. 2009 Aug 15;69(16):6463-72. doi: 10.1158/0008-5472.CAN-08-3363. Cancer Res. 2009. PMID: 19679546 Free PMC article.

2

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

Mullany LK, Fan HY, Liu Z, White LD, Marshall A, Gunaratne P, Anderson ML, Creighton CJ, Xin L, Deavers M, Wong KK, Richards JS. Mullany LK, et al. Among authors: liu z. Oncogene. 2011 Aug 11;30(32):3522-36. doi: 10.1038/onc.2011.70. Epub 2011 Mar 21. Oncogene. 2011. PMID: 21423204 Free PMC article.

3

Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones.

Ren YA, Mullany LK, Liu Z, Herron AJ, Wong KK, Richards JS. Ren YA, et al. Among authors: liu z. Cancer Res. 2016 Apr 15;76(8):2206-18. doi: 10.1158/0008-5472.CAN-15-1046. Epub 2016 Mar 10. Cancer Res. 2016. PMID: 26964623 Free PMC article.

4

Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation.

Fan HY, Shimada M, Liu Z, Cahill N, Noma N, Wu Y, Gossen J, Richards JS. Fan HY, et al. Among authors: liu z. Development. 2008 Jun;135(12):2127-37. doi: 10.1242/dev.020560. Development. 2008. PMID: 18506027 Free PMC article.

5

Targeted disruption of Pten in ovarian granulosa cells enhances ovulation and extends the life span of luteal cells.

Fan HY, Liu Z, Cahill N, Richards JS. Fan HY, et al. Among authors: liu z. Mol Endocrinol. 2008 Sep;22(9):2128-40. doi: 10.1210/me.2008-0095. Epub 2008 Jul 7. Mol Endocrinol. 2008. PMID: 18606860 Free PMC article.

6

MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.

Fan HY, Liu Z, Shimada M, Sterneck E, Johnson PF, Hedrick SM, Richards JS. Fan HY, et al. Among authors: liu z. Science. 2009 May 15;324(5929):938-41. doi: 10.1126/science.1171396. Science. 2009. PMID: 19443782 Free PMC article.

7

Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility.

Liu Z, Fan HY, Wang Y, Richards JS. Liu Z, et al. Mol Endocrinol. 2010 Sep;24(9):1794-804. doi: 10.1210/me.2010-0086. Epub 2010 Jul 7. Mol Endocrinol. 2010. PMID: 20610537 Free PMC article.

8

Consequences of RAS and MAPK activation in the ovary: the good, the bad and the ugly.

Fan HY, Liu Z, Mullany LK, Richards JS. Fan HY, et al. Among authors: liu z. Mol Cell Endocrinol. 2012 Jun 5;356(1-2):74-9. doi: 10.1016/j.mce.2011.12.005. Epub 2011 Dec 16. Mol Cell Endocrinol. 2012. PMID: 22197887 Free PMC article. Review.

9

Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis.

Richards JS, Fan HY, Liu Z, Tsoi M, Laguë MN, Boyer A, Boerboom D. Richards JS, et al. Among authors: liu z. Oncogene. 2012 Mar 22;31(12):1504-20. doi: 10.1038/onc.2011.341. Epub 2011 Aug 22. Oncogene. 2012. PMID: 21860425 Free PMC article.

10

FOXO1/3 depletion in granulosa cells alters follicle growth, death and regulation of pituitary FSH.

Liu Z, Castrillon DH, Zhou W, Richards JS. Liu Z, et al. Mol Endocrinol. 2013 Feb;27(2):238-52. doi: 10.1210/me.2012-1296. Epub 2013 Jan 15. Mol Endocrinol. 2013. PMID: 23322722 Free PMC article.

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