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Ethanolic extract of Casearia sylvestris and its clerodane diterpen (caseargrewiin F) protect against DNA damage at low concentrations and cause DNA damage at high concentrations in mice's blood cells.
de Oliveira AM, dos Santos AG, Dos Santos RA, Csipak AR, Olivato C, da Silva IC, de Freitas MB, Bassi CL, Cavalheiro AJ, Bolzani VS, Silva DH, Sakamoto-Hojo ET, Takahashi CS, Soares CP. de Oliveira AM, et al. Among authors: cavalheiro aj. Mutagenesis. 2009 Nov;24(6):501-6. doi: 10.1093/mutage/gep034. Epub 2009 Sep 7. Mutagenesis. 2009. PMID: 19736218
Cytotoxic clerodane diterpenoids from Casearia obliqua.
Vieira GM Jr, Gonçalves Tde O, Regasini LO, Ferreira PM, Pessoa Cdo O, Costa Lotufo LV, Torres RB, Boralle N, Bolzani Vda S, Cavalheiro AJ. Vieira GM Jr, et al. Among authors: cavalheiro aj. J Nat Prod. 2009 Oct;72(10):1847-50. doi: 10.1021/np9004079. J Nat Prod. 2009. PMID: 19788290
Casearin X, its degradation product and other clerodane diterpenes from leaves of Casearia sylvestris: evaluation of cytotoxicity against normal and tumor human cells.
dos Santos AG, Ferreira PM, Vieira Júnior GM, Perez CC, Gomes Tininis A, Silva GH, Bolzani Vda S, Costa-Lotufo LV, Pessoa Cdo O, Cavalheiro AJ. dos Santos AG, et al. Among authors: cavalheiro aj. Chem Biodivers. 2010 Jan;7(1):205-15. doi: 10.1002/cbdv.200800342. Chem Biodivers. 2010. PMID: 20087991
Casearin X exhibits cytotoxic effects in leukemia cells triggered by apoptosis.
Ferreira PM, Santos AG, Tininis AG, Costa PM, Cavalheiro AJ, Bolzani VS, Moraes MO, Costa-Lotufo LV, Montenegro RC, Pessoa C. Ferreira PM, et al. Among authors: cavalheiro aj. Chem Biol Interact. 2010 Dec 5;188(3):497-504. doi: 10.1016/j.cbi.2010.08.008. Chem Biol Interact. 2010. PMID: 20816779 Free article.
An unprecedented neolignan skeleton from Chimarrhis turbinata.
Cardoso CL, Castro-Gamboa I, Bergamini GM, Cavalheiro AJ, Silva DH, Lopes MN, Araújo AR, Furlan M, Verli H, Bolzani Vda S. Cardoso CL, et al. Among authors: cavalheiro aj. J Nat Prod. 2011 Mar 25;74(3):487-91. doi: 10.1021/np1007476. Epub 2011 Feb 22. J Nat Prod. 2011. PMID: 21341711
Cytotoxic clerodane diterpenes from Casearia rupestris.
Vieira-Júnior GM, Dutra LA, Ferreira PM, de Moraes MO, Costa Lotufo LV, Pessoa Cdo Ó, Torres RB, Boralle N, Bolzani Vda S, Cavalheiro AJ. Vieira-Júnior GM, et al. Among authors: cavalheiro aj. J Nat Prod. 2011 Apr 25;74(4):776-81. doi: 10.1021/np100840w. Epub 2011 Mar 7. J Nat Prod. 2011. PMID: 21381705
Folk uses and pharmacological properties of Casearia sylvestris: a medicinal review.
Ferreira PM, Costa-Lotufo LV, Moraes MO, Barros FW, Martins AM, Cavalheiro AJ, Bolzani VS, Santos AG, Pessoa C. Ferreira PM, et al. Among authors: cavalheiro aj. An Acad Bras Cienc. 2011 Dec;83(4):1373-84. doi: 10.1590/s0001-37652011005000040. Epub 2011 Oct 7. An Acad Bras Cienc. 2011. PMID: 22159347 Free article.
Chemopreventive activity of compounds extracted from Casearia sylvestris (Salicaceae) Sw against DNA damage induced by particulate matter emitted by sugarcane burning near Araraquara, Brazil.
Prieto AM, Santos AG, Csipak AR, Caliri CM, Silva IC, Arbex MA, Silva FS, Marchi MR, Cavalheiro AJ, Silva DH, Bolzani VS, Soares CP. Prieto AM, et al. Among authors: cavalheiro aj. Toxicol Appl Pharmacol. 2012 Dec 15;265(3):368-72. doi: 10.1016/j.taap.2012.09.005. Epub 2012 Sep 13. Toxicol Appl Pharmacol. 2012. PMID: 22982620 Free article.
73 results