Spinelli R - Search Results

1

Phase I pharmacokinetic and pharmacodynamic study of the aurora kinase inhibitor danusertib in patients with advanced or metastatic solid tumors.

Steeghs N, Eskens FA, Gelderblom H, Verweij J, Nortier JW, Ouwerkerk J, van Noort C, Mariani M, Spinelli R, Carpinelli P, Laffranchi B, de Jonge MJ. Steeghs N, et al. Among authors: spinelli r. J Clin Oncol. 2009 Oct 20;27(30):5094-101. doi: 10.1200/JCO.2008.21.6655. Epub 2009 Sep 21. J Clin Oncol. 2009. PMID: 19770380 Clinical Trial.

2

A prolonged methoxymorpholino doxorubicin (PNU-152243 or MMRDX) infusion schedule in patients with solid tumours: a phase 1 and pharmacokinetic study.

Fokkema E, Verweij J, van Oosterom AT, Uges DR, Spinelli R, Valota O, de Vries EG, Groen HJ. Fokkema E, et al. Among authors: spinelli r. Br J Cancer. 2000 Feb;82(4):767-71. doi: 10.1054/bjoc.1999.0996. Br J Cancer. 2000. PMID: 10732743 Free PMC article. Clinical Trial.

3

A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin.

Schoemaker NE, van Kesteren C, Rosing H, Jansen S, Swart M, Lieverst J, Fraier D, Breda M, Pellizzoni C, Spinelli R, Grazia Porro M, Beijnen JH, Schellens JH, ten Bokkel Huinink WW. Schoemaker NE, et al. Among authors: spinelli r. Br J Cancer. 2002 Sep 9;87(6):608-14. doi: 10.1038/sj.bjc.6600516. Br J Cancer. 2002. PMID: 12237769 Free PMC article. Clinical Trial.

4

Phase I and pharmacokinetic (PK) study of MAG-CPT (PNU 166148): a polymeric derivative of camptothecin (CPT).

Bissett D, Cassidy J, de Bono JS, Muirhead F, Main M, Robson L, Fraier D, Magnè ML, Pellizzoni C, Porro MG, Spinelli R, Speed W, Twelves C. Bissett D, et al. Among authors: spinelli r. Br J Cancer. 2004 Jul 5;91(1):50-5. doi: 10.1038/sj.bjc.6601922. Br J Cancer. 2004. PMID: 15187995 Free PMC article. Clinical Trial.

5

The effects of degree of hepatic or renal impairment on the pharmacokinetics of exemestane in postmenopausal women.

Jannuzzo MG, Poggesi I, Spinelli R, Rocchetti M, Cicioni P, Buchan P. Jannuzzo MG, et al. Among authors: spinelli r. Cancer Chemother Pharmacol. 2004 Jun;53(6):475-81. doi: 10.1007/s00280-004-0774-5. Epub 2004 Mar 11. Cancer Chemother Pharmacol. 2004. PMID: 15014897

6

Species-differences in disposition and reductive metabolism of methoxymorpholinodoxorubicin (PNU 152243), a new potential anticancer agent.

Breda M, Benedetti MS, Battaglia R, Castelli MG, Poggesi I, Spinelli R, Hackett AM, Dostert P. Breda M, et al. Among authors: spinelli r. Pharmacol Res. 2000 Feb;41(2):239-48. doi: 10.1006/phrs.1999.0584. Pharmacol Res. 2000. PMID: 10623492

7

Estrogen suppression in premenopausal women following 8 weeks of treatment with exemestane and triptorelin versus triptorelin alone.

Jannuzzo MG, Di Salle E, Spinelli R, Pirotta N, Buchan P, Bello A. Jannuzzo MG, et al. Among authors: spinelli r. Breast Cancer Res Treat. 2009 Feb;113(3):491-9. doi: 10.1007/s10549-008-9949-9. Epub 2008 Mar 11. Breast Cancer Res Treat. 2009. PMID: 18330698 Clinical Trial.

8

A study of the pharmacokinetics and tolerability of ritipenem acoxil in healthy volunteers following multiple oral dosing.

Poggesi I, Spinelli R, Frigerio E, Strolin Benedetti M, Carra L, Sassella D, Rimoldi R. Poggesi I, et al. Among authors: spinelli r. J Antimicrob Chemother. 1997 Aug;40(2):291-4. doi: 10.1093/jac/40.2.291. J Antimicrob Chemother. 1997. PMID: 9301999

9

A predictive model for exemestane pharmacokinetics/pharmacodynamics incorporating the effect of food and formulation.

Valle M, Di Salle E, Jannuzzo MG, Poggesi I, Rocchetti M, Spinelli R, Verotta D. Valle M, et al. Among authors: spinelli r. Br J Clin Pharmacol. 2005 Mar;59(3):355-64. doi: 10.1111/j.1365-2125.2005.02335.x. Br J Clin Pharmacol. 2005. PMID: 15752382 Free PMC article. Clinical Trial.

10

Rare Primitive Lung Adenocarcinoma in Larynx: A Case Report.

Maglione MG, Salzano G, Maffia F, Spinelli R, Carraturo E, De Cecio R, Ionna F. Maglione MG, et al. Among authors: spinelli r. Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5925-5929. doi: 10.1007/s12070-024-04993-1. Epub 2024 Aug 24. Indian J Otolaryngol Head Neck Surg. 2024. PMID: 39559106 Free PMC article.

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