Stratford IJ - Search Results

1

The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts.

Shannon AM, Telfer BA, Smith PD, Babur M, Logie A, Wilkinson RW, Debray C, Stratford IJ, Williams KJ, Wedge SR. Shannon AM, et al. Among authors: stratford ij. Clin Cancer Res. 2009 Nov 1;15(21):6619-29. doi: 10.1158/1078-0432.CCR-08-2958. Epub 2009 Oct 20. Clin Cancer Res. 2009. PMID: 19843666 Free article.

2

Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: reversing tumor radioresistance and effecting cure.

Cowen RL, Williams KJ, Chinje EC, Jaffar M, Sheppard FC, Telfer BA, Wind NS, Stratford IJ. Cowen RL, et al. Among authors: stratford ij. Cancer Res. 2004 Feb 15;64(4):1396-402. doi: 10.1158/0008-5472.can-03-2698. Cancer Res. 2004. PMID: 14973055

3

ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity.

Williams KJ, Telfer BA, Brave S, Kendrew J, Whittaker L, Stratford IJ, Wedge SR. Williams KJ, et al. Among authors: stratford ij. Clin Cancer Res. 2004 Dec 15;10(24):8587-93. doi: 10.1158/1078-0432.CCR-04-1147. Clin Cancer Res. 2004. PMID: 15623642

4

Tirapazamine administered as a neoadjuvant to radiotherapy reduces metastatic dissemination.

Lunt SJ, Telfer BA, Fitzmaurice RJ, Stratford IJ, Williams KJ. Lunt SJ, et al. Among authors: stratford ij. Clin Cancer Res. 2005 Jun 1;11(11):4212-6. doi: 10.1158/1078-0432.CCR-04-2162. Clin Cancer Res. 2005. PMID: 15930359 Free article.

5

Combining radiotherapy with AZD2171, a potent inhibitor of vascular endothelial growth factor signaling: pathophysiologic effects and therapeutic benefit.

Williams KJ, Telfer BA, Shannon AM, Babur M, Stratford IJ, Wedge SR. Williams KJ, et al. Among authors: stratford ij. Mol Cancer Ther. 2007 Feb;6(2):599-606. doi: 10.1158/1535-7163.MCT-06-0508. Mol Cancer Ther. 2007. PMID: 17308057 Free article.

6

In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts.

Williams KJ, Albertella MR, Fitzpatrick B, Loadman PM, Shnyder SD, Chinje EC, Telfer BA, Dunk CR, Harris PA, Stratford IJ. Williams KJ, et al. Among authors: stratford ij. Mol Cancer Ther. 2009 Dec;8(12):3266-75. doi: 10.1158/1535-7163.MCT-09-0396. Mol Cancer Ther. 2009. PMID: 19996276

7

Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft.

Senra JM, Telfer BA, Cherry KE, McCrudden CM, Hirst DG, O'Connor MJ, Wedge SR, Stratford IJ. Senra JM, et al. Among authors: stratford ij. Mol Cancer Ther. 2011 Oct;10(10):1949-58. doi: 10.1158/1535-7163.MCT-11-0278. Epub 2011 Aug 8. Mol Cancer Ther. 2011. PMID: 21825006 Free PMC article.

8

Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport.

Bola BM, Chadwick AL, Michopoulos F, Blount KG, Telfer BA, Williams KJ, Smith PD, Critchlow SE, Stratford IJ. Bola BM, et al. Among authors: stratford ij. Mol Cancer Ther. 2014 Dec;13(12):2805-16. doi: 10.1158/1535-7163.MCT-13-1091. Epub 2014 Oct 3. Mol Cancer Ther. 2014. PMID: 25281618 Free PMC article.

9

ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model.

Williams KJ, Telfer BA, Stratford IJ, Wedge SR. Williams KJ, et al. Among authors: stratford ij. Br J Cancer. 2002 Apr 8;86(7):1157-61. doi: 10.1038/sj.bjc.6600182. Br J Cancer. 2002. PMID: 11953865 Free PMC article.

10

Inhibition of vascular endothelial growth factor signalling using cediranib (RECENTIN; AZD2171) enhances radiation response and causes substantial physiological changes in lung tumour xenografts.

Williams KJ, Telfer BA, Shannon AM, Babur M, Stratford IJ, Wedge SR. Williams KJ, et al. Among authors: stratford ij. Br J Radiol. 2008 Oct;81 Spec No 1:S21-7. doi: 10.1259/bjr/59853976. Br J Radiol. 2008. PMID: 18819995

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