Schober WD - Search Results

1

Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML.

Carter BZ, Mak DH, Schober WD, Koller E, Pinilla C, Vassilev LT, Reed JC, Andreeff M. Carter BZ, et al. Among authors: schober wd. Blood. 2010 Jan 14;115(2):306-14. doi: 10.1182/blood-2009-03-212563. Epub 2009 Nov 6. Blood. 2010. PMID: 19897582 Free PMC article.

2

Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells.

Carter BZ, Mak PY, Mak DH, Ruvolo VR, Schober W, McQueen T, Cortes J, Kantarjian HM, Champlin RE, Konopleva M, Andreeff M. Carter BZ, et al. Oncotarget. 2015 Oct 13;6(31):30487-99. doi: 10.18632/oncotarget.5890. Oncotarget. 2015. PMID: 26431162 Free PMC article.

3

Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells.

Carter BZ, Mak DH, Woessner R, Gross S, Schober WD, Estrov Z, Kantarjian H, Andreeff M. Carter BZ, et al. Among authors: schober wd. Leukemia. 2009 Oct;23(10):1755-62. doi: 10.1038/leu.2009.101. Epub 2009 May 21. Leukemia. 2009. PMID: 19458629 Free PMC article.

4

Activation of apoptosis signaling eliminates CD34+ progenitor cells in blast crisis CML independent of response to tyrosine kinase inhibitors.

Mak DH, Wang RY, Schober WD, Konopleva M, Cortes J, Kantarjian H, Andreeff M, Carter BZ. Mak DH, et al. Among authors: schober wd. Leukemia. 2012 Apr;26(4):788-94. doi: 10.1038/leu.2011.285. Epub 2011 Oct 28. Leukemia. 2012. PMID: 22033489 Free PMC article.

5

Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia.

Milella M, Estrov Z, Kornblau SM, Carter BZ, Konopleva M, Tari A, Schober WD, Harris D, Leysath CE, Lopez-Berestein G, Huang Z, Andreeff M. Milella M, et al. Among authors: schober wd. Blood. 2002 May 1;99(9):3461-4. doi: 10.1182/blood.v99.9.3461. Blood. 2002. PMID: 11964319 Free article.

6

Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis.

Carter BZ, Kornblau SM, Tsao T, Wang RY, Schober WD, Milella M, Sung HG, Reed JC, Andreeff M. Carter BZ, et al. Among authors: schober wd. Blood. 2003 Dec 1;102(12):4179-86. doi: 10.1182/blood-2003-03-0960. Epub 2003 Aug 14. Blood. 2003. PMID: 12920030 Free article.

7

Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.

Carter BZ, Gronda M, Wang Z, Welsh K, Pinilla C, Andreeff M, Schober WD, Nefzi A, Pond GR, Mawji IA, Houghten RA, Ostresh J, Brandwein J, Minden MD, Schuh AC, Wells RA, Messner H, Chun K, Reed JC, Schimmer AD. Carter BZ, et al. Among authors: schober wd. Blood. 2005 May 15;105(10):4043-50. doi: 10.1182/blood-2004-08-3168. Epub 2005 Feb 1. Blood. 2005. PMID: 15687241 Free PMC article.

8

Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells.

Carter BZ, Mak DH, Schober WD, Cabreira-Hansen M, Beran M, McQueen T, Chen W, Andreeff M. Carter BZ, et al. Among authors: schober wd. Blood. 2006 Feb 15;107(4):1555-63. doi: 10.1182/blood-2004-12-4704. Epub 2005 Oct 27. Blood. 2006. PMID: 16254145 Free PMC article.

9

Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.

Carter BZ, Mak DH, Schober WD, McQueen T, Harris D, Estrov Z, Evans RL, Andreeff M. Carter BZ, et al. Among authors: schober wd. Blood. 2006 Jul 15;108(2):630-7. doi: 10.1182/blood-2005-09-3898. Epub 2006 Mar 23. Blood. 2006. PMID: 16556893 Free PMC article.

10

Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance.

Carter BZ, Mak DH, Shi Y, Schober WD, Wang RY, Konopleva M, Koller E, Dean NM, Andreeff M. Carter BZ, et al. Among authors: schober wd. Cell Cycle. 2006 Oct;5(19):2223-9. doi: 10.4161/cc.5.19.3255. Epub 2006 Oct 1. Cell Cycle. 2006. PMID: 16969080

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