Dagger SA - Search Results

1

Unaltered negative selection and Treg development of self-reactive thymocytes in TCR transgenic Fyn-deficient mice.

Mamchak AA, Thien CB, Dagger SA, Lyandres J, Jiang S, Langdon WY, DeFranco AL. Mamchak AA, et al. Among authors: dagger sa. Eur J Immunol. 2010 Feb;40(2):539-47. doi: 10.1002/eji.200939645. Eur J Immunol. 2010. PMID: 19904769 Free PMC article.

2

The Cbl-b RING finger domain has a limited role in regulating inflammatory cytokine production by IgE-activated mast cells.

Oksvold MP, Dagger SA, Thien CB, Langdon WY. Oksvold MP, et al. Among authors: dagger sa. Mol Immunol. 2008 Feb;45(4):925-36. doi: 10.1016/j.molimm.2007.08.002. Epub 2007 Sep 14. Mol Immunol. 2008. PMID: 17868870

3

c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.

Thien CB, Dagger SA, Steer JH, Koentgen F, Jansen ES, Scott CL, Langdon WY. Thien CB, et al. Among authors: dagger sa. J Biol Chem. 2010 Apr 2;285(14):10969-81. doi: 10.1074/jbc.M109.094920. Epub 2010 Feb 4. J Biol Chem. 2010. PMID: 20133944 Free PMC article.

4

Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice.

Duyvestyn JM, Taylor SJ, Dagger SA, Orandle M, Morse HC 3rd, Thien CB, Langdon WY. Duyvestyn JM, et al. Among authors: dagger sa. PLoS One. 2014 Apr 9;9(4):e94717. doi: 10.1371/journal.pone.0094717. eCollection 2014. PLoS One. 2014. PMID: 24718698 Free PMC article.

5

Loss of c-Cbl E3 ubiquitin ligase activity enhances the development of myeloid leukemia in FLT3-ITD mutant mice.

Taylor SJ, Thien CB, Dagger SA, Duyvestyn JM, Grove CS, Lee BH, Gilliland DG, Langdon WY. Taylor SJ, et al. Among authors: dagger sa. Exp Hematol. 2015 Mar;43(3):191-206.e1. doi: 10.1016/j.exphem.2014.11.009. Epub 2014 Dec 19. Exp Hematol. 2015. PMID: 25534201 Free article.

6

Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling.

Taylor SJ, Dagger SA, Thien CB, Wikstrom ME, Langdon WY. Taylor SJ, et al. Among authors: dagger sa. Blood. 2012 Nov 8;120(19):4049-57. doi: 10.1182/blood-2012-06-436675. Epub 2012 Sep 18. Blood. 2012. PMID: 22990016 Free article.

7

The targeting of human and mouse B lymphocytes by dasatinib.

Oksvold MP, Duyvestyn JM, Dagger SA, Taylor SJ, Forfang L, Myklebust JH, Smeland EB, Langdon WY. Oksvold MP, et al. Among authors: dagger sa. Exp Hematol. 2015 May;43(5):352-363.e4. doi: 10.1016/j.exphem.2015.01.008. Epub 2015 Jan 29. Exp Hematol. 2015. PMID: 25641047 Free article.

8

Dasatinib promotes the activation of quiescent hematopoietic stem cells in mice.

Duyvestyn JM, Taylor SJ, Dagger SA, Langdon WY. Duyvestyn JM, et al. Among authors: dagger sa. Exp Hematol. 2016 May;44(5):410-421.e5. doi: 10.1016/j.exphem.2016.02.008. Epub 2016 Feb 26. Exp Hematol. 2016. PMID: 26921649 Free article.

9

Preventing chemotherapy-induced myelosuppression by repurposing the FLT3 inhibitor quizartinib.

Taylor SJ, Duyvestyn JM, Dagger SA, Dishington EJ, Rinaldi CA, Dovey OM, Vassiliou GS, Grove CS, Langdon WY. Taylor SJ, et al. Among authors: dagger sa. Sci Transl Med. 2017 Aug 9;9(402):eaam8060. doi: 10.1126/scitranslmed.aam8060. Sci Transl Med. 2017. PMID: 28794285

10

Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma.

Smeets MF, Chan AC, Dagger S, Bradley CK, Wei A, Izon DJ. Smeets MF, et al. PLoS One. 2013 May 7;8(5):e62346. doi: 10.1371/journal.pone.0062346. Print 2013. PLoS One. 2013. PMID: 23667468 Free PMC article.

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