DeFranco AL - Search Results

1

Unaltered negative selection and Treg development of self-reactive thymocytes in TCR transgenic Fyn-deficient mice.

Mamchak AA, Thien CB, Dagger SA, Lyandres J, Jiang S, Langdon WY, DeFranco AL. Mamchak AA, et al. Among authors: defranco al. Eur J Immunol. 2010 Feb;40(2):539-47. doi: 10.1002/eji.200939645. Eur J Immunol. 2010. PMID: 19904769 Free PMC article.

2

Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells.

Mamchak AA, Sullivan BM, Hou B, Lee LM, Gilden JK, Krummel MF, Locksley RM, DeFranco AL. Mamchak AA, et al. Among authors: defranco al. J Immunol. 2008 Oct 15;181(8):5374-85. doi: 10.4049/jimmunol.181.8.5374. J Immunol. 2008. PMID: 18832694 Free PMC article.

3

Signaling mutations and autoimmunity.

Yu CC, Mamchak AA, DeFranco AL. Yu CC, et al. Among authors: defranco al. Curr Dir Autoimmun. 2003;6:61-88. doi: 10.1159/000066856. Curr Dir Autoimmun. 2003. PMID: 12408047 Review.

4

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance.

Gross AJ, Lyandres JR, Panigrahi AK, Prak ET, DeFranco AL. Gross AJ, et al. Among authors: defranco al. J Immunol. 2009 May 1;182(9):5382-92. doi: 10.4049/jimmunol.0803941. J Immunol. 2009. PMID: 19380785 Free PMC article.

5

Inhibition of the MEK/ERK signaling pathway blocks a subset of B cell responses to antigen.

Richards JD, Davé SH, Chou CH, Mamchak AA, DeFranco AL. Richards JD, et al. Among authors: defranco al. J Immunol. 2001 Mar 15;166(6):3855-64. doi: 10.4049/jimmunol.166.6.3855. J Immunol. 2001. PMID: 11238629

6

Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.

Gross AJ, Proekt I, DeFranco AL. Gross AJ, et al. Among authors: defranco al. Eur J Immunol. 2011 Dec;41(12):3645-55. doi: 10.1002/eji.201141708. Epub 2011 Nov 10. Eur J Immunol. 2011. PMID: 21928281 Free PMC article.

7

Positive and negative roles of the tyrosine kinase Lyn in B cell function.

DeFranco AL, Chan VW, Lowell CA. DeFranco AL, et al. Semin Immunol. 1998 Aug;10(4):299-307. doi: 10.1006/smim.1998.0122. Semin Immunol. 1998. PMID: 9695186 Review.

8

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

Wheeler ML, Defranco AL. Wheeler ML, et al. Among authors: defranco al. J Immunol. 2012 Nov 1;189(9):4405-16. doi: 10.4049/jimmunol.1201433. Epub 2012 Sep 28. J Immunol. 2012. PMID: 23024271 Free PMC article.

9

APOBEC3 enzymes restrict marginal zone B cells.

Beck-Engeser GB, Winkelmann R, Wheeler ML, Shansab M, Yu P, Wünsche S, Walchhütter A, Metzner M, Vettermann C, Eilat D, DeFranco A, Jäck HM, Wabl M. Beck-Engeser GB, et al. Eur J Immunol. 2015 Mar;45(3):695-704. doi: 10.1002/eji.201445218. Epub 2015 Jan 21. Eur J Immunol. 2015. PMID: 25501566 Free PMC article.

10

Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics.

Gupta N, Wollscheid B, Watts JD, Scheer B, Aebersold R, DeFranco AL. Gupta N, et al. Among authors: defranco al. Nat Immunol. 2006 Jun;7(6):625-33. doi: 10.1038/ni1337. Epub 2006 Apr 30. Nat Immunol. 2006. PMID: 16648854

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