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Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance.
Preiss S, Littlejohn M, Angus P, Thompson A, Desmond P, Lewin SR, Sasadeusz J, Matthews G, Dore GJ, Shaw T, Sozzi V, Yuen L, Lau G, Ayres A, Thio C, Avihingsanon A, Ruxrungtham K, Locarnini S, Revill PA. Preiss S, et al. Among authors: revill pa. Hepatology. 2008 Sep;48(3):741-9. doi: 10.1002/hep.22386. Hepatology. 2008. PMID: 18571815 Free PMC article.
HBV mutations in untreated HIV-HBV co-infection using genomic length sequencing.
Audsley J, Littlejohn M, Yuen L, Sasadeusz J, Ayres A, Desmond C, Spelman T, Lau G, Matthews GV, Avihingsanon A, Seaberg E, Philp F, Saulynas M, Ruxrungtham K, Dore GJ, Locarnini SA, Thio CL, Lewin SR, Revill PA. Audsley J, et al. Among authors: revill pa. Virology. 2010 Sep 30;405(2):539-47. doi: 10.1016/j.virol.2010.06.038. Epub 2010 Jul 23. Virology. 2010. PMID: 20655563 Free PMC article.
Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease.
Desmond CP, Gaudieri S, James IR, Pfafferott K, Chopra A, Lau GK, Audsley J, Day C, Chivers S, Gordon A, Revill PA, Bowden S, Ayres A, Desmond PV, Thompson AJ, Roberts SK, Locarnini SA, Mallal SA, Lewin SR. Desmond CP, et al. Among authors: revill pa. J Virol. 2012 Jan;86(2):1181-92. doi: 10.1128/JVI.05308-11. Epub 2011 Nov 9. J Virol. 2012. PMID: 22072755 Free PMC article.
110 results