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Page 1
Nuclear translocation of urokinase-type plasminogen activator.
Stepanova V, Lebedeva T, Kuo A, Yarovoi S, Tkachuk S, Zaitsev S, Bdeir K, Dumler I, Marks MS, Parfyonova Y, Tkachuk VA, Higazi AA, Cines DB. Stepanova V, et al. Blood. 2008 Jul 1;112(1):100-10. doi: 10.1182/blood-2007-07-104455. Epub 2008 Mar 12. Blood. 2008. PMID: 18337556 Free PMC article.
Urokinase-type plasminogen activator (uPA) induces pulmonary microvascular endothelial permeability through low density lipoprotein receptor-related protein (LRP)-dependent activation of endothelial nitric-oxide synthase.
Makarova AM, Lebedeva TV, Nassar T, Higazi AA, Xue J, Carinato ME, Bdeir K, Cines DB, Stepanova V. Makarova AM, et al. Among authors: stepanova v. J Biol Chem. 2011 Jul 1;286(26):23044-53. doi: 10.1074/jbc.M110.210195. Epub 2011 May 3. J Biol Chem. 2011. PMID: 21540184 Free PMC article.
A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.
Fuentes RE, Zaitsev S, Ahn HS, Hayes V, Kowalska MA, Lambert MP, Wang Y, Siegel DL, Bougie DW, Aster RH, Myers DD, Stepanova V, Cines DB, Muzykantov VR, Poncz M. Fuentes RE, et al. Among authors: stepanova v. J Clin Invest. 2016 Feb;126(2):483-94. doi: 10.1172/JCI81470. J Clin Invest. 2016. PMID: 26690701 Free PMC article.
Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.
Stepanova V, Jayaraman PS, Zaitsev SV, Lebedeva T, Bdeir K, Kershaw R, Holman KR, Parfyonova YV, Semina EV, Beloglazova IB, Tkachuk VA, Cines DB. Stepanova V, et al. J Biol Chem. 2016 Jul 15;291(29):15029-45. doi: 10.1074/jbc.M115.678490. Epub 2016 May 4. J Biol Chem. 2016. PMID: 27151212 Free PMC article.
FcRn augments induction of tissue factor activity by IgG-containing immune complexes.
Cines DB, Zaitsev S, Rauova L, Rux AH, Stepanova V, Krishnaswamy S, Sarkar A, Kowalska MA, Zhao G, Mast AE, Blumberg LJ, McCrae KR, Poncz M, Hubbard JJ, Pyzik M, Blumberg RS. Cines DB, et al. Among authors: stepanova v. Blood. 2020 Jun 4;135(23):2085-2093. doi: 10.1182/blood.2019001133. Blood. 2020. PMID: 32187355 Free PMC article.
Urokinase-type plasminogen activator (uPA) is critical for progression of tuberous sclerosis complex 2 (TSC2)-deficient tumors.
Stepanova V, Dergilev KV, Holman KR, Parfyonova YV, Tsokolaeva ZI, Teter M, Atochina-Vasserman EN, Volgina A, Zaitsev SV, Lewis SP, Zabozlaev FG, Obraztsova K, Krymskaya VP, Cines DB. Stepanova V, et al. J Biol Chem. 2017 Dec 15;292(50):20528-20543. doi: 10.1074/jbc.M117.799593. Epub 2017 Sep 27. J Biol Chem. 2017. PMID: 28972182 Free PMC article.
Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia.
Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Cines DB, et al. Among authors: stepanova v. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. Blood Adv. 2016. PMID: 29296696 Free PMC article.
144 results