Murphy RC - Search Results

1

Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.

Thomas CP, Morgan LT, Maskrey BH, Murphy RC, Kühn H, Hazen SL, Goodall AH, Hamali HA, Collins PW, O'Donnell VB. Thomas CP, et al. Among authors: murphy rc. J Biol Chem. 2010 Mar 5;285(10):6891-903. doi: 10.1074/jbc.M109.078428. Epub 2010 Jan 8. J Biol Chem. 2010. PMID: 20061396 Free PMC article.

2

Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid.

Hinz C, Aldrovandi M, Uhlson C, Marnett LJ, Longhurst HJ, Warner TD, Alam S, Slatter DA, Lauder SN, Allen-Redpath K, Collins PW, Murphy RC, Thomas CP, O'Donnell VB. Hinz C, et al. Among authors: murphy rc. J Biol Chem. 2016 Jun 24;291(26):13448-64. doi: 10.1074/jbc.M115.700609. Epub 2016 Apr 22. J Biol Chem. 2016. PMID: 27129261 Free PMC article.

3

New families of bioactive oxidized phospholipids generated by immune cells: identification and signaling actions.

O'Donnell VB, Murphy RC. O'Donnell VB, et al. Among authors: murphy rc. Blood. 2012 Sep 6;120(10):1985-92. doi: 10.1182/blood-2012-04-402826. Epub 2012 Jul 16. Blood. 2012. PMID: 22802337 Free PMC article. Review.

4

Revising the structure of a new eicosanoid from human platelets to 8,9-11,12-diepoxy-13-hydroxyeicosadienoic acid.

Kornilov A, Kennedy PD, Aldrovandi M, Watson AJA, Hinz C, Harless B, Colombo J, Maxey KM, Tyrrell VJ, Simon M, Aggarwal VK, Boeglin WE, Brash AR, Murphy RC, O'Donnell VB. Kornilov A, et al. Among authors: murphy rc. J Biol Chem. 2019 Jun 7;294(23):9225-9238. doi: 10.1074/jbc.RA119.008915. Epub 2019 May 6. J Biol Chem. 2019. PMID: 31061099 Free PMC article.

5

DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression.

Aldrovandi M, Hinz C, Lauder SN, Podmore H, Hornshaw M, Slatter DA, Tyrrell VJ, Clark SR, Marnett LJ, Collins PW, Murphy RC, O'Donnell VB. Aldrovandi M, et al. Among authors: murphy rc. Redox Biol. 2017 Apr;11:663-672. doi: 10.1016/j.redox.2017.01.001. Epub 2017 Jan 13. Redox Biol. 2017. PMID: 28160743 Free PMC article.

6

Quantitative assays for esterified oxylipins generated by immune cells.

Morgan AH, Hammond VJ, Morgan L, Thomas CP, Tallman KA, Garcia-Diaz YR, McGuigan C, Serpi M, Porter NA, Murphy RC, O'Donnell VB. Morgan AH, et al. Among authors: murphy rc. Nat Protoc. 2010 Dec;5(12):1919-31. doi: 10.1038/nprot.2010.162. Epub 2010 Nov 10. Nat Protoc. 2010. PMID: 21127486 Free PMC article.

7

Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation.

Clark SR, Thomas CP, Hammond VJ, Aldrovandi M, Wilkinson GW, Hart KW, Murphy RC, Collins PW, O'Donnell VB. Clark SR, et al. Among authors: murphy rc. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5875-80. doi: 10.1073/pnas.1222419110. Epub 2013 Mar 25. Proc Natl Acad Sci U S A. 2013. PMID: 23530199 Free PMC article.

8

Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation.

Aldrovandi M, Hammond VJ, Podmore H, Hornshaw M, Clark SR, Marnett LJ, Slatter DA, Murphy RC, Collins PW, O'Donnell VB. Aldrovandi M, et al. Among authors: murphy rc. J Lipid Res. 2013 Nov;54(11):3085-97. doi: 10.1194/jlr.M041533. Epub 2013 Jul 24. J Lipid Res. 2013. PMID: 23883581 Free PMC article.

9

Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets.

O'Donnell VB, Murphy RC, Watson SP. O'Donnell VB, et al. Among authors: murphy rc. Circ Res. 2014 Mar 28;114(7):1185-203. doi: 10.1161/CIRCRESAHA.114.301597. Circ Res. 2014. PMID: 24677238 Free PMC article. Review.

10

Enzymatically oxidized phospholipids assume center stage as essential regulators of innate immunity and cell death.

O'Donnell VB, Aldrovandi M, Murphy RC, Krönke G. O'Donnell VB, et al. Among authors: murphy rc. Sci Signal. 2019 Mar 26;12(574):eaau2293. doi: 10.1126/scisignal.aau2293. Sci Signal. 2019. PMID: 30914483 Review.

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