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Page 1
15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers.
Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, Gauderman WJ, Crowell RE, Tesfaigzi Y, Stidley CA, Amos CI, Siegfried JM, Gilliland FD, Belinsky SA. Leng S, et al. Among authors: stidley ca. J Natl Cancer Inst. 2015 Feb 23;107(5):djv035. doi: 10.1093/jnci/djv035. J Natl Cancer Inst. 2015. PMID: 25713168 Free PMC article.
Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.
Leng S, Wu G, Collins LB, Thomas CL, Tellez CS, Jauregui AR, Picchi MA, Zhang X, Juri DE, Desai D, Amin SG, Crowell RE, Stidley CA, Liu Y, Swenberg JA, Lin Y, Wathelet MG, Gilliland FD, Belinsky SA. Leng S, et al. Among authors: stidley ca. Cancer Res. 2015 Aug 1;75(15):3108-17. doi: 10.1158/0008-5472.CAN-15-0243. Epub 2015 Jul 16. Cancer Res. 2015. PMID: 26183928 Free PMC article.
Gene promoter methylation in plasma and sputum increases with lung cancer risk.
Belinsky SA, Klinge DM, Dekker JD, Smith MW, Bocklage TJ, Gilliland FD, Crowell RE, Karp DD, Stidley CA, Picchi MA. Belinsky SA, et al. Among authors: stidley ca. Clin Cancer Res. 2005 Sep 15;11(18):6505-11. doi: 10.1158/1078-0432.CCR-05-0625. Clin Cancer Res. 2005. PMID: 16166426
The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, Crowell RE, Belinsky SA. Leng S, et al. Among authors: stidley ca. Clin Cancer Res. 2011 Apr 1;17(7):2014-23. doi: 10.1158/1078-0432.CCR-10-3026. Epub 2011 Feb 25. Clin Cancer Res. 2011. PMID: 21355081 Free PMC article.
Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study.
Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, Tesfaigzi Y, Gilliland FD, Belinsky SA. Leng S, et al. Among authors: stidley ca. Cancer Res. 2012 Feb 1;72(3):707-15. doi: 10.1158/0008-5472.CAN-11-3194. Epub 2011 Dec 2. Cancer Res. 2012. PMID: 22139380 Free PMC article.
86 results