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WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells.
Tang Y, Simoneau AR, Liao WX, Yi G, Hope C, Liu F, Li S, Xie J, Holcombe RF, Jurnak FA, Mercola D, Hoang BH, Zi X. Tang Y, et al. Among authors: xie j. Mol Cancer Ther. 2009 Feb;8(2):458-68. doi: 10.1158/1535-7163.MCT-08-0885. Epub 2009 Jan 27. Mol Cancer Ther. 2009. PMID: 19174556 Free PMC article.
The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition.
Yee DS, Tang Y, Li X, Liu Z, Guo Y, Ghaffar S, McQueen P, Atreya D, Xie J, Simoneau AR, Hoang BH, Zi X. Yee DS, et al. Among authors: xie j. Mol Cancer. 2010 Jun 23;9:162. doi: 10.1186/1476-4598-9-162. Mol Cancer. 2010. PMID: 20573255 Free PMC article.
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