Dragin N - Search Results

1

Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.

Shi Z, Dragin N, Miller ML, Stringer KF, Johansson E, Chen J, Uno S, Gonzalez FJ, Rubio CA, Nebert DW. Shi Z, et al. Among authors: dragin n. Int J Cancer. 2010 Nov 15;127(10):2334-50. doi: 10.1002/ijc.25222. Int J Cancer. 2010. PMID: 20127859 Free PMC article.

2

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: dragin n. Mol Pharmacol. 2006 Apr;69(4):1103-14. doi: 10.1124/mol.105.021501. Epub 2005 Dec 23. Mol Pharmacol. 2006. PMID: 16377763

3

For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.

Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW. Dragin N, et al. J Biol Chem. 2006 Jul 7;281(27):18591-600. doi: 10.1074/jbc.M601159200. Epub 2006 Apr 24. J Biol Chem. 2006. PMID: 16636061 Free article.

4

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

Uno S, Dragin N, Miller ML, Dalton TP, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: dragin n. Free Radic Biol Med. 2008 Feb 15;44(4):570-83. doi: 10.1016/j.freeradbiomed.2007.10.044. Epub 2007 Nov 12. Free Radic Biol Med. 2008. PMID: 17997381 Free PMC article.

5

Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.

Dragin N, Shi Z, Madan R, Karp CL, Sartor MA, Chen C, Gonzalez FJ, Nebert DW. Dragin N, et al. Mol Pharmacol. 2008 Jun;73(6):1844-56. doi: 10.1124/mol.108.045658. Epub 2008 Mar 27. Mol Pharmacol. 2008. PMID: 18372398 Free PMC article.

6

Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene.

Shi Z, Dragin N, Gálvez-Peralta M, Jorge-Nebert LF, Miller ML, Wang B, Nebert DW. Shi Z, et al. Among authors: dragin n. Mol Pharmacol. 2010 Jul;78(1):46-57. doi: 10.1124/mol.110.063438. Epub 2010 Apr 6. Mol Pharmacol. 2010. PMID: 20371670 Free PMC article.

7

Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm.

Nebert DW, Shi Z, Gálvez-Peralta M, Uno S, Dragin N. Nebert DW, et al. Among authors: dragin n. Mol Pharmacol. 2013 Sep;84(3):304-13. doi: 10.1124/mol.113.086637. Epub 2013 Jun 12. Mol Pharmacol. 2013. PMID: 23761301 Free PMC article. Review.

8

Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.

Derkenne S, Curran CP, Shertzer HG, Dalton TP, Dragin N, Nebert DW. Derkenne S, et al. Among authors: dragin n. Pharmacogenet Genomics. 2005 Jul;15(7):503-11. doi: 10.1097/01.fpc.0000167326.00411.50. Pharmacogenet Genomics. 2005. PMID: 15970798

9

Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs.

Genter MB, Marlowe J, Kevin Kerzee J, Dragin N, Puga A, Dalton TP, Nebert DW. Genter MB, et al. Among authors: dragin n. Biochem Biophys Res Commun. 2006 Sep 15;348(1):120-3. doi: 10.1016/j.bbrc.2006.07.025. Epub 2006 Jul 14. Biochem Biophys Res Commun. 2006. PMID: 16876762

10

Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.

Wang B, Schneider SN, Dragin N, Girijashanker K, Dalton TP, He L, Miller ML, Stringer KF, Soleimani M, Richardson DD, Nebert DW. Wang B, et al. Among authors: dragin n. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1523-35. doi: 10.1152/ajpcell.00409.2006. Epub 2006 Nov 15. Am J Physiol Cell Physiol. 2007. PMID: 17108009 Free article.

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