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PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
Halaban R, Zhang W, Bacchiocchi A, Cheng E, Parisi F, Ariyan S, Krauthammer M, McCusker JP, Kluger Y, Sznol M. Halaban R, et al. Among authors: kluger y. Pigment Cell Melanoma Res. 2010 Apr;23(2):190-200. doi: 10.1111/j.1755-148X.2010.00685.x. Epub 2010 Feb 10. Pigment Cell Melanoma Res. 2010. PMID: 20149136 Free PMC article.
Phosphatidylinositol-3-kinase as a therapeutic target in melanoma.
Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM. Aziz SA, et al. Among authors: kluger y, kluger hm. Clin Cancer Res. 2009 May 1;15(9):3029-36. doi: 10.1158/1078-0432.CCR-08-2768. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383818 Free PMC article.
Plasma markers for identifying patients with metastatic melanoma.
Kluger HM, Hoyt K, Bacchiocchi A, Mayer T, Kirsch J, Kluger Y, Sznol M, Ariyan S, Molinaro A, Halaban R. Kluger HM, et al. Among authors: kluger y. Clin Cancer Res. 2011 Apr 15;17(8):2417-25. doi: 10.1158/1078-0432.CCR-10-2402. Epub 2011 Apr 12. Clin Cancer Res. 2011. PMID: 21487066 Free PMC article.
Integrated analysis of tumor samples sheds light on tumor heterogeneity.
Parisi F, Micsinai M, Strino F, Ariyan S, Narayan D, Bacchiocchi A, Cheng E, Xu F, Li P, Kluger H, Halaban R, Kluger Y. Parisi F, et al. Among authors: kluger h, kluger y. Yale J Biol Med. 2012 Sep;85(3):347-61. Epub 2012 Sep 25. Yale J Biol Med. 2012. PMID: 23012583 Free PMC article.
535 results