Lowenstein PR - Search Results

1

Study of the efficacy, biodistribution, and safety profile of therapeutic gutless adenovirus vectors as a prelude to a phase I clinical trial for glioblastoma.

Muhammad AK, Puntel M, Candolfi M, Salem A, Yagiz K, Farrokhi C, Kroeger KM, Xiong W, Curtin JF, Liu C, Lawrence K, Bondale NS, Lerner J, Baker GJ, Foulad D, Pechnick RN, Palmer D, Ng P, Lowenstein PR, Castro MG. Muhammad AK, et al. Among authors: lowenstein pr. Clin Pharmacol Ther. 2010 Aug;88(2):204-13. doi: 10.1038/clpt.2009.260. Epub 2010 Feb 17. Clin Pharmacol Ther. 2010. PMID: 20164833 Free PMC article.

2

Antibodies to neuropeptide precursors expressed as fusion proteins in E. coli. Their use to examine neuropeptide biosynthetic pathways, intracellular trafficking and physiological activities.

Castro MG, Lowry PJ, Lowenstein PR. Castro MG, et al. Among authors: lowenstein pr. Int J Biochem. 1992 Jun;24(6):847-60. doi: 10.1016/0020-711x(92)90089-j. Int J Biochem. 1992. PMID: 1612176 Review. No abstract available.

3

Adenovirus vectors to transfer genes into neurones: implications for gene therapy of neurological disorders.

Bain D, Wilkinson GW, Preston CM, Castro MG, Lowenstein PR. Bain D, et al. Among authors: lowenstein pr. Gene Ther. 1994;1 Suppl 1:S68. Gene Ther. 1994. PMID: 8542414 No abstract available.

4

Cell type-specific expression in brain cell cultures from a short human cytomegalovirus major immediate early promoter depends on whether it is inserted into herpesvirus or adenovirus vectors.

Shering AF, Bain D, Stewart K, Epstein AL, Castro MG, Wilkinson GW, Lowenstein PR. Shering AF, et al. Among authors: lowenstein pr. J Gen Virol. 1997 Feb;78 ( Pt 2):445-59. doi: 10.1099/0022-1317-78-2-445. J Gen Virol. 1997. PMID: 9018068

5

Expression of transgenes in normal and neoplastic anterior pituitary cells using recombinant adenoviruses: long term expression, cell cycle dependency, and effects on hormone secretion.

Castro MG, Goya RG, Sosa YE, Rowe J, Larregina A, Morelli A, Lowenstein PR. Castro MG, et al. Among authors: lowenstein pr. Endocrinology. 1997 May;138(5):2184-94. doi: 10.1210/endo.138.5.5134. Endocrinology. 1997. PMID: 9112418

6

FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors.

Larregina AT, Morelli AE, Dewey RA, Castro MG, Fontana A, Lowenstein PR. Larregina AT, et al. Among authors: lowenstein pr. Gene Ther. 1998 Apr;5(4):563-8. doi: 10.1038/sj.gt.3300615. Gene Ther. 1998. PMID: 9614583

7

Use of recombinant herpes simplex virus type 1 vectors for gene transfer into tumour and normal anterior pituitary cells.

Goya RG, Rowe J, Sosa YE, Tomasec P, Lowenstein PR, Castro MG. Goya RG, et al. Among authors: lowenstein pr. Mol Cell Endocrinol. 1998 Apr 30;139(1-2):199-207. doi: 10.1016/s0303-7207(98)00059-8. Mol Cell Endocrinol. 1998. PMID: 9705088

8

Gene therapy for inherited neurological disorders: towards therapeutic intervention in the Lesch-Nyhan syndrome.

Lowenstein PR, Southgate TD, Smith-Arica JR, Smith J, Castro MG. Lowenstein PR, et al. Prog Brain Res. 1998;117:485-501. doi: 10.1016/s0079-6123(08)64034-0. Prog Brain Res. 1998. PMID: 9932427 Review. No abstract available.

9

Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain.

Cartmell T, Southgate T, Rees GS, Castro MG, Lowenstein PR, Luheshi GN. Cartmell T, et al. Among authors: lowenstein pr. J Neurosci. 1999 Feb 15;19(4):1517-23. doi: 10.1523/JNEUROSCI.19-04-01517.1999. J Neurosci. 1999. PMID: 9952427 Free PMC article.

10

Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity.

Morelli AE, Larregina AT, Smith-Arica J, Dewey RA, Southgate TD, Ambar B, Fontana A, Castro MG, Lowenstein PR. Morelli AE, et al. Among authors: lowenstein pr. J Gen Virol. 1999 Mar;80 ( Pt 3):571-583. doi: 10.1099/0022-1317-80-3-571. J Gen Virol. 1999. PMID: 10091995

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