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RCAI-8, 9, 18, 19, and 49-52, conformationally restricted analogues of KRN7000 with an azetidine or a pyrrolidine ring: Their synthesis and bioactivity for mouse natural killer T cells to produce cytokines.
Fuhshuku K, Hongo N, Tashiro T, Masuda Y, Nakagawa R, Seino K, Taniguchi M, Mori K. Fuhshuku K, et al. Among authors: taniguchi m. Bioorg Med Chem. 2008 Jan 15;16(2):950-64. doi: 10.1016/j.bmc.2007.10.008. Epub 2007 Oct 10. Bioorg Med Chem. 2008. PMID: 17950609
RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines.
Tashiro T, Hongo N, Nakagawa R, Seino K, Watarai H, Ishii Y, Taniguchi M, Mori K. Tashiro T, et al. Among authors: taniguchi m. Bioorg Med Chem. 2008 Oct 1;16(19):8896-906. doi: 10.1016/j.bmc.2008.08.060. Epub 2008 Aug 29. Bioorg Med Chem. 2008. PMID: 18790646
Adjuvant activity mediated by iNKT cells.
Fujii S, Motohashi S, Shimizu K, Nakayama T, Yoshiga Y, Taniguchi M. Fujii S, et al. Among authors: taniguchi m. Semin Immunol. 2010 Apr;22(2):97-102. doi: 10.1016/j.smim.2009.10.002. Epub 2009 Nov 24. Semin Immunol. 2010. PMID: 19939703 Review.
3,165 results