Zage PE - Search Results

1

Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.

Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV. Nilsson MB, et al. Among authors: zage pe. Oncogene. 2010 May 20;29(20):2938-49. doi: 10.1038/onc.2010.60. Epub 2010 Mar 8. Oncogene. 2010. PMID: 20208561

2

A phase II trial of nifurtimox combined with topotecan and cyclophosphamide for refractory or relapsed neuroblastoma and medulloblastoma.

Eslin D, Zage PE, Bergendahl G, Lewis E, Roberts W, Kraveka J, Mitchell D, Isakoff MS, Rawwas J, Wada RK, Fluchel M, Brown VI, Ginn K, Higgins T, BeeravallyNagulapally A, Dykema K, Hanna G, Ferguson W, Saulnier Sholler GL. Eslin D, et al. Among authors: zage pe. Int J Cancer. 2023 Sep 1;153(5):1026-1034. doi: 10.1002/ijc.34569. Epub 2023 May 29. Int J Cancer. 2023. PMID: 37246577 Clinical Trial.

3

Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway.

Thress K, Macintyre T, Wang H, Whitston D, Liu ZY, Hoffmann E, Wang T, Brown JL, Webster K, Omer C, Zage PE, Zeng L, Zweidler-McKay PA. Thress K, et al. Among authors: zage pe. Mol Cancer Ther. 2009 Jul;8(7):1818-27. doi: 10.1158/1535-7163.MCT-09-0036. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509272

4

A novel therapeutic combination for neuroblastoma: the vascular endothelial growth factor receptor/epidermal growth factor receptor/rearranged during transfection inhibitor vandetanib with 13-cis-retinoic acid.

Zage PE, Zeng L, Palla S, Fang W, Nilsson MB, Heymach JV, Zweidler-McKay PA. Zage PE, et al. Cancer. 2010 May 15;116(10):2465-75. doi: 10.1002/cncr.25017. Cancer. 2010. PMID: 20225331 Free article.

5

Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo.

Richards KN, Zweidler-McKay PA, Van Roy N, Speleman F, Trevino J, Zage PE, Hughes DP. Richards KN, et al. Among authors: zage pe. Cancer. 2010 Jul 1;116(13):3233-43. doi: 10.1002/cncr.25073. Cancer. 2010. PMID: 20564646 Free PMC article.

6

The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma.

Levy AG, Zage PE, Akers LJ, Ghisoli ML, Chen Z, Fang W, Kannan S, Graham T, Zeng L, Franklin AR, Huang P, Zweidler-McKay PA. Levy AG, et al. Among authors: zage pe. Invest New Drugs. 2012 Feb;30(1):191-9. doi: 10.1007/s10637-010-9551-y. Epub 2010 Oct 5. Invest New Drugs. 2012. PMID: 20890785 Free PMC article.

7

The selective Trk inhibitor AZ623 inhibits brain-derived neurotrophic factor-mediated neuroblastoma cell proliferation and signaling and is synergistic with topotecan.

Zage PE, Graham TC, Zeng L, Fang W, Pien C, Thress K, Omer C, Brown JL, Zweidler-McKay PA. Zage PE, et al. Cancer. 2011 Mar 15;117(6):1321-91. doi: 10.1002/cncr.25674. Epub 2010 Oct 19. Cancer. 2011. PMID: 20960503 Free article.

8

Notch pathway activation induces neuroblastoma tumor cell growth arrest.

Zage PE, Nolo R, Fang W, Stewart J, Garcia-Manero G, Zweidler-McKay PA. Zage PE, et al. Pediatr Blood Cancer. 2012 May;58(5):682-9. doi: 10.1002/pbc.23202. Epub 2011 Jul 8. Pediatr Blood Cancer. 2012. PMID: 21744479 Free PMC article.

9

Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines.

Das CM, Zage PE, Taylor P, Aguilera D, Wolff JE, Lee D, Gopalakrishnan V. Das CM, et al. Among authors: zage pe. Eur J Cancer. 2010 Oct;46(15):2771-80. doi: 10.1016/j.ejca.2010.05.010. Eur J Cancer. 2010. PMID: 20886683 Free PMC article.

10

Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCF(β-TRCP) in neuroblastoma cells.

Singh A, Rokes C, Gireud M, Fletcher S, Baumgartner J, Fuller G, Stewart J, Zage P, Gopalakrishnan V. Singh A, et al. Cancer. 2011 Nov 15;117(22):5189-202. doi: 10.1002/cncr.26145. Epub 2011 Apr 26. Cancer. 2011. PMID: 21523764 Free article.

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