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Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo.
Mayer-Barber KD, Barber DL, Shenderov K, White SD, Wilson MS, Cheever A, Kugler D, Hieny S, Caspar P, Núñez G, Schlueter D, Flavell RA, Sutterwala FS, Sher A. Mayer-Barber KD, et al. Among authors: barber dl. J Immunol. 2010 Apr 1;184(7):3326-30. doi: 10.4049/jimmunol.0904189. Epub 2010 Mar 3. J Immunol. 2010. PMID: 20200276 Free PMC article.
Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.
Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, Sher A. Shenderov K, et al. Among authors: barber dl. J Immunol. 2013 Jun 1;190(11):5722-30. doi: 10.4049/jimmunol.1203343. Epub 2013 Apr 29. J Immunol. 2013. PMID: 23630357 Free PMC article.
267 results