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The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1.
J Biol Chem. 2014 Jun 20;289(25):17802-11. doi: 10.1074/jbc.M114.548172. Epub 2014 May 8.
J Biol Chem. 2014.
PMID: 24811167
Free PMC article.
Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage.
Lopez H, Zhang L, George NM, Liu X, Pang X, Evans JJD, Targy NM, Luo X.
Lopez H, et al. Among authors: evans jjd.
J Biol Chem. 2010 May 14;285(20):15016-15026. doi: 10.1074/jbc.M109.086231. Epub 2010 Mar 11.
J Biol Chem. 2010.
PMID: 20223826
Free PMC article.
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Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.
George NM, Targy N, Evans JJ, Zhang L, Luo X.
George NM, et al.
J Biol Chem. 2010 Jan 8;285(2):1384-92. doi: 10.1074/jbc.M109.049924. Epub 2009 Oct 30.
J Biol Chem. 2010.
PMID: 19880508
Free PMC article.
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A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax.
George NM, Evans JJ, Luo X.
George NM, et al.
Genes Dev. 2007 Aug 1;21(15):1937-48. doi: 10.1101/gad.1553607.
Genes Dev. 2007.
PMID: 17671092
Free PMC article.
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