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PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.
Lin RC, Weeks KL, Gao XM, Williams RB, Bernardo BC, Kiriazis H, Matthews VB, Woodcock EA, Bouwman RD, Mollica JP, Speirs HJ, Dawes IW, Daly RJ, Shioi T, Izumo S, Febbraio MA, Du XJ, McMullen JR. Lin RC, et al. Among authors: izumo s. Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):724-32. doi: 10.1161/ATVBAHA.109.201988. Arterioscler Thromb Vasc Biol. 2010. PMID: 20237330
Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy.
McMullen JR, Amirahmadi F, Woodcock EA, Schinke-Braun M, Bouwman RD, Hewitt KA, Mollica JP, Zhang L, Zhang Y, Shioi T, Buerger A, Izumo S, Jay PY, Jennings GL. McMullen JR, et al. Among authors: izumo s. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):612-7. doi: 10.1073/pnas.0606663104. Epub 2007 Jan 3. Proc Natl Acad Sci U S A. 2007. PMID: 17202264 Free PMC article.
Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation.
Pretorius L, Du XJ, Woodcock EA, Kiriazis H, Lin RC, Marasco S, Medcalf RL, Ming Z, Head GA, Tan JW, Cemerlang N, Sadoshima J, Shioi T, Izumo S, Lukoshkova EV, Dart AM, Jennings GL, McMullen JR. Pretorius L, et al. Among authors: izumo s. Am J Pathol. 2009 Sep;175(3):998-1009. doi: 10.2353/ajpath.2009.090126. Epub 2009 Aug 13. Am J Pathol. 2009. PMID: 19679877 Free PMC article.
Akt/protein kinase B promotes organ growth in transgenic mice.
Shioi T, McMullen JR, Kang PM, Douglas PS, Obata T, Franke TF, Cantley LC, Izumo S. Shioi T, et al. Among authors: izumo s. Mol Cell Biol. 2002 Apr;22(8):2799-809. doi: 10.1128/MCB.22.8.2799-2809.2002. Mol Cell Biol. 2002. PMID: 11909972 Free PMC article.
Rapamycin attenuates load-induced cardiac hypertrophy in mice.
Shioi T, McMullen JR, Tarnavski O, Converso K, Sherwood MC, Manning WJ, Izumo S. Shioi T, et al. Among authors: izumo s. Circulation. 2003 Apr 1;107(12):1664-70. doi: 10.1161/01.CIR.0000057979.36322.88. Epub 2003 Mar 17. Circulation. 2003. PMID: 12668503
Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function.
Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM. Rigor DL, et al. Among authors: izumo s. Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H566-72. doi: 10.1152/ajpheart.00562.2008. Epub 2009 Jan 2. Am J Physiol Heart Circ Physiol. 2009. PMID: 19122165 Free PMC article.
387 results