Umezawa K - Search Results

1

Dehydroxymethylepoxyquinomicin inhibits expression and production of inflammatory mediators in interleukin-1beta-induced human chondrocytes.

Cardile V, Frasca G, Libra M, Caggia S, Umezawa K, Panico A, Malaponte G. Cardile V, et al. Among authors: umezawa k. Cell Physiol Biochem. 2010;25(4-5):543-50. doi: 10.1159/000303058. Epub 2010 Mar 23. Cell Physiol Biochem. 2010. PMID: 20332635 Free article.

2

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, prevents inflammatory injury induced by interferon-gamma and histamine in NCTC 2544 keratinocytes.

Cardile V, Libra M, Caggia S, Frasca G, Umezawa K, Stivala F, Mazzarino MC, Bevelacqua Y, Coco M, Malaponte G. Cardile V, et al. Among authors: umezawa k. Clin Exp Pharmacol Physiol. 2010 Jul;37(7):679-83. doi: 10.1111/j.1440-1681.2010.05375.x. Epub 2010 Mar 12. Clin Exp Pharmacol Physiol. 2010. PMID: 20337659

3

Suppression of inflammatory cytokine secretion by an NF-ĸB inhibitor DHMEQ in nasal polyps fibroblasts.

Valera FC, Umezawa K, Brassesco MS, Castro-Gamero AM, Queiroz RG, Scrideli CA, Tone LG, Anselmo-Lima WT. Valera FC, et al. Among authors: umezawa k. Cell Physiol Biochem. 2012;30(1):13-22. doi: 10.1159/000339042. Epub 2012 Jun 5. Cell Physiol Biochem. 2012. PMID: 22759952 Free article.

4

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-κB inhibitor, reduces chemokines and adhesion molecule expression induced by IL-1β in human corneal fibroblasts.

Inokawa S, Watanabe T, Keino H, Sato Y, Hirakata A, Okada AA, Fukuda K, Fukushima A, Umezawa K. Inokawa S, et al. Among authors: umezawa k. Graefes Arch Clin Exp Ophthalmol. 2015 Apr;253(4):557-63. doi: 10.1007/s00417-014-2879-9. Epub 2014 Dec 18. Graefes Arch Clin Exp Ophthalmol. 2015. PMID: 25519802

5

Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism.

Lampiasi N, Azzolina A, D'Alessandro N, Umezawa K, McCubrey JA, Montalto G, Cervello M. Lampiasi N, et al. Among authors: umezawa k. Mol Pharmacol. 2009 Aug;76(2):290-300. doi: 10.1124/mol.109.055418. Epub 2009 May 20. Mol Pharmacol. 2009. PMID: 19461054

6

A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice.

Funakoshi T, Yamashita K, Ichikawa N, Fukai M, Suzuki T, Goto R, Oura T, Kobayashi N, Katsurada T, Ichihara S, Ozaki M, Umezawa K, Todo S. Funakoshi T, et al. Among authors: umezawa k. J Crohns Colitis. 2012 Mar;6(2):215-25. doi: 10.1016/j.crohns.2011.08.011. Epub 2011 Sep 21. J Crohns Colitis. 2012. PMID: 22325176

7

Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin.

Starenki DV, Namba H, Saenko VA, Ohtsuru A, Maeda S, Umezawa K, Yamashita S. Starenki DV, et al. Among authors: umezawa k. Clin Cancer Res. 2004 Oct 15;10(20):6821-9. doi: 10.1158/1078-0432.CCR-04-0463. Clin Cancer Res. 2004. PMID: 15501958

8

Dehydroxymethylepoxyquinomicin (DHMEQ) can suppress tumour necrosis factor-α production in lipopolysaccharide-injected mice, resulting in rescuing mice from death in vivo.

Shimo T, Adachi Y, Umezawa K, Okigaki M, Takaya J, Taniuchi S, Ikehara S, Kaneko K. Shimo T, et al. Among authors: umezawa k. Clin Exp Immunol. 2011 Nov;166(2):299-306. doi: 10.1111/j.1365-2249.2011.04475.x. Clin Exp Immunol. 2011. PMID: 21985376 Free PMC article.

9

Inhibition of macrophage activation and phagocytosis by a novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin.

Suzuki E, Umezawa K. Suzuki E, et al. Among authors: umezawa k. Biomed Pharmacother. 2006 Nov;60(9):578-86. doi: 10.1016/j.biopha.2006.07.089. Epub 2006 Sep 1. Biomed Pharmacother. 2006. PMID: 16978829

10

Dehydroxymethylepoxyquinomicin (DHMEQ), a novel NF-kappaB inhibitor, inhibits allergic inflammation and airway remodelling in murine models of asthma.

Shimizu K, Konno S, Ozaki M, Umezawa K, Yamashita K, Todo S, Nishimura M. Shimizu K, et al. Among authors: umezawa k. Clin Exp Allergy. 2012 Aug;42(8):1273-81. doi: 10.1111/j.1365-2222.2012.04007.x. Clin Exp Allergy. 2012. PMID: 22805475

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