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A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation.
Taaffe J, Chahroudi A, Engram J, Sumpter B, Meeker T, Ratcliffe S, Paiardini M, Else J, Silvestri G. Taaffe J, et al. Among authors: sumpter b. J Virol. 2010 Jun;84(11):5476-84. doi: 10.1128/JVI.00039-10. Epub 2010 Mar 24. J Virol. 2010. PMID: 20335252 Free PMC article.
Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.
Engram JC, Dunham RM, Makedonas G, Vanderford TH, Sumpter B, Klatt NR, Ratcliffe SJ, Garg S, Paiardini M, McQuoid M, Altman JD, Staprans SI, Betts MR, Garber DA, Feinberg MB, Silvestri G. Engram JC, et al. Among authors: sumpter b. J Immunol. 2009 Jul 1;183(1):706-17. doi: 10.4049/jimmunol.0803746. J Immunol. 2009. PMID: 19542473
The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.
Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, Pandrea I, Apetrei C, Sodora DL, Staprans SI, Feinberg MB, Silvestri G. Dunham R, et al. Among authors: sumpter b. Blood. 2006 Jul 1;108(1):209-17. doi: 10.1182/blood-2005-12-4897. Epub 2006 Mar 7. Blood. 2006. PMID: 16522814 Free PMC article.
Cell-cycle dysregulation in the immunopathogenesis of AIDS.
Paiardini M, Cervasi B, Dunham R, Sumpter B, Radziewicz H, Silvestri G. Paiardini M, et al. Among authors: sumpter b. Immunol Res. 2004;29(1-3):253-68. doi: 10.1385/IR:29:1-3:253. Immunol Res. 2004. PMID: 15181287 Review.
251 results