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The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors.
Cheng H, Hoffman J, Le P, Nair SK, Cripps S, Matthews J, Smith C, Yang M, Kupchinsky S, Dress K, Edwards M, Cole B, Walters E, Loh C, Ermolieff J, Fanjul A, Bhat GB, Herrera J, Pauly T, Hosea N, Paderes G, Rejto P. Cheng H, et al. Among authors: herrera j. Bioorg Med Chem Lett. 2010 May 1;20(9):2897-902. doi: 10.1016/j.bmcl.2010.03.032. Epub 2010 Mar 10. Bioorg Med Chem Lett. 2010. PMID: 20363126
Demonstration of proof of mechanism and pharmacokinetics and pharmacodynamic relationship with 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide (PF-915275), an inhibitor of 11 -hydroxysteroid dehydrogenase type 1, in cynomolgus monkeys.
Bhat BG, Hosea N, Fanjul A, Herrera J, Chapman J, Thalacker F, Stewart PM, Rejto PA. Bhat BG, et al. Among authors: herrera j. J Pharmacol Exp Ther. 2008 Jan;324(1):299-305. doi: 10.1124/jpet.107.128280. Epub 2007 Oct 5. J Pharmacol Exp Ther. 2008. PMID: 17921190
BRIVA-ONE study: 12-month outcomes of brivaracetam monotherapy in clinical practice.
Villanueva V, Villar EG, Fernandez-Cabrera A, Zurita J, Lopez-Gonzalez FJ, Rodríguez-Osorio X, Parejo-Carbonell B, Estevez JC, Mercedes-Alvarez B, Ojeda J, Rubio-Roy M, Garcia-Escrivá A, Gómez-Ibáñez A, Martinez-Poles J, Martinez-Agredano P, Calle R, Sierra-Marcos A, Gonzalez AM, Herrera JD, Rodriguez-Uranga J, Cabezas B, Martinez E, Renau J, de Toledo M, Hampel KG, Alarcón C, Barceló MI, Monterde A, Lara LB, Sansa G, Serratosa JM. Villanueva V, et al. Among authors: herrera jd. Epilepsia Open. 2024 Oct 29. doi: 10.1002/epi4.13078. Online ahead of print. Epilepsia Open. 2024. PMID: 39470722 Free article.
1,119 results