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Population pharmacokinetics of esaxerenone, a novel non-steroidal mineralocorticoid receptor blocker, in patients with essential hypertension, patients with diabetic nephropathy, and healthy volunteers.
Yoshihara K, Fukae M, Kastrissios H, Wada R, Shimizu T, Ishizuka H. Yoshihara K, et al. Among authors: kastrissios h. Drug Metab Pharmacokinet. 2023 Oct;52:100516. doi: 10.1016/j.dmpk.2023.100516. Epub 2023 Jun 7. Drug Metab Pharmacokinet. 2023. PMID: 37690271 Free article.
Exposure-Response Relationships in Patients With HER2-Positive Metastatic Breast Cancer and Other Solid Tumors Treated With Trastuzumab Deruxtecan.
Yin O, Iwata H, Lin CC, Tamura K, Watanabe J, Wada R, Kastrissios H, AbuTarif M, Garimella T, Lee C, Zhang L, Shahidi J, LaCreta F. Yin O, et al. Among authors: kastrissios h. Clin Pharmacol Ther. 2021 Oct;110(4):986-996. doi: 10.1002/cpt.2291. Epub 2021 Jun 10. Clin Pharmacol Ther. 2021. PMID: 33999422 Free PMC article.
Reporting guidelines for population pharmacokinetic analyses.
Dykstra K, Mehrotra N, Tornøe CW, Kastrissios H, Patel B, Al-Huniti N, Jadhav P, Wang Y, Byon W. Dykstra K, et al. Among authors: kastrissios h. J Clin Pharmacol. 2015 Aug;55(8):875-87. doi: 10.1002/jcph.532. J Clin Pharmacol. 2015. PMID: 26148467
Reporting guidelines for population pharmacokinetic analyses.
Dykstra K, Mehrotra N, Tornøe CW, Kastrissios H, Patel B, Al-Huniti N, Jadhav P, Wang Y, Byon W. Dykstra K, et al. Among authors: kastrissios h. J Pharmacokinet Pharmacodyn. 2015 Jun;42(3):301-14. doi: 10.1007/s10928-015-9417-1. Epub 2015 Apr 30. J Pharmacokinet Pharmacodyn. 2015. PMID: 25925797 Free PMC article.
Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis.
Hasegawa C, Kastrissios H, Monteleone J, Ohno T, Umemura T, Ohyama M, Nagase S, Small M, Deacon S, Ogawa M, Ieiri I. Hasegawa C, et al. Among authors: kastrissios h. J Clin Pharmacol. 2014 Aug;54(8):937-48. doi: 10.1002/jcph.279. Epub 2014 Feb 28. J Clin Pharmacol. 2014. PMID: 24615681 Clinical Trial.
42 results