Raven J - Search Results

1

A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo.

Williams P, Rafei M, Bouchentouf M, Raven J, Yuan S, Cuerquis J, Forner KA, Birman E, Galipeau J. Williams P, et al. Among authors: raven j. Mol Ther. 2010 Jul;18(7):1293-301. doi: 10.1038/mt.2010.49. Epub 2010 Apr 13. Mol Ther. 2010. PMID: 20389285 Free PMC article.

2

Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation.

Raven JF, Williams V, Wang S, Tremblay ML, Muller WJ, Durbin JE, Koromilas AE. Raven JF, et al. Cell Cycle. 2011 Mar 1;10(5):794-804. doi: 10.4161/cc.10.5.14956. Epub 2011 Mar 1. Cell Cycle. 2011. PMID: 21311224

3

Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1.

Wang S, Raven JF, Durbin JE, Koromilas AE. Wang S, et al. PLoS One. 2008;3(10):e3476. doi: 10.1371/journal.pone.0003476. Epub 2008 Oct 22. PLoS One. 2008. PMID: 18941537 Free PMC article.

4

The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase.

Wang S, Raven JF, Baltzis D, Kazemi S, Brunet DV, Hatzoglou M, Tremblay ML, Koromilas AE. Wang S, et al. J Biol Chem. 2006 Apr 7;281(14):9439-49. doi: 10.1074/jbc.M504977200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431927 Free article.

5

A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.

Kazemi S, Mounir Z, Baltzis D, Raven JF, Wang S, Krishnamoorthy JL, Pluquet O, Pelletier J, Koromilas AE. Kazemi S, et al. Among authors: raven jf. Mol Biol Cell. 2007 Sep;18(9):3635-44. doi: 10.1091/mbc.e07-01-0053. Epub 2007 Jun 27. Mol Biol Cell. 2007. PMID: 17596516 Free PMC article.

6

STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells.

Wang S, Raven JF, Koromilas AE. Wang S, et al. Mol Cancer Res. 2010 May;8(5):798-805. doi: 10.1158/1541-7786.MCR-10-0027. Epub 2010 Apr 20. Mol Cancer Res. 2010. PMID: 20407011

7

Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2.

Su Q, Wang S, Baltzis D, Qu LK, Raven JF, Li S, Wong AH, Koromilas AE. Su Q, et al. EMBO Rep. 2007 Mar;8(3):265-70. doi: 10.1038/sj.embor.7400891. Epub 2007 Feb 9. EMBO Rep. 2007. PMID: 17290288 Free PMC article.

8

The eIF2alpha kinases inhibit vesicular stomatitis virus replication independently of eIF2alpha phosphorylation.

Krishnamoorthy J, Mounir Z, Raven JF, Koromilas AE. Krishnamoorthy J, et al. Among authors: raven jf. Cell Cycle. 2008 Aug;7(15):2346-51. doi: 10.4161/cc.6323. Epub 2008 May 21. Cell Cycle. 2008. PMID: 18677106

9

PERK and PKR: old kinases learn new tricks.

Raven JF, Koromilas AE. Raven JF, et al. Cell Cycle. 2008 May 1;7(9):1146-50. doi: 10.4161/cc.7.9.5811. Epub 2008 Feb 21. Cell Cycle. 2008. PMID: 18418049 Review.

10

PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylation.

Raven JF, Baltzis D, Wang S, Mounir Z, Papadakis AI, Gao HQ, Koromilas AE. Raven JF, et al. J Biol Chem. 2008 Feb 8;283(6):3097-3108. doi: 10.1074/jbc.M709677200. Epub 2007 Dec 6. J Biol Chem. 2008. PMID: 18063576 Free article.

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